Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/K08F8.4
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Query: K08F8.4 CE21050 locus:bas-2 phenylalanine-4-hydroxylase (PH4H) status:Confirmed SW:P90925 protein_id:CAA91286.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
biopterin_H Biopterin-dependent aromatic amino acid h 802.6 8.4e-248 1
ACT ACT domain 40.6 5e-10 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
ACT 1/1 30 107 .. 1 75 [] 40.6 5e-10
biopterin_H 1/1 119 452 .. 1 334 [] 802.6 8.4e-248
Alignments of top-scoring domains:
ACT: domain 1 of 1, from 30 to 107: score 40.6, E = 5e-10
*->tvlevevpDrPGlLarvfsaLaergiNIesisqgtsedeeddg.aii
t+++++++ + G+La+ ++++ +++N+ +i++++s+ + ++ +
K08F8.4 30 TTIVFTLREKAGALAETLKLFQAHDVNLSHIESRPSK----THeGCY 72
sfvvd.....deedleealeaLkk.lvdvvkvvdv<-*
+ v+ + +d ++e ++e +++ + v v+d+
K08F8.4 73 EVLVEfaeaeDHRKIEGVIEHFQQkAEKKVLVQDW 107
biopterin_H: domain 1 of 1, from 119 to 452: score 802.6, E = 8.4e-248
*->pWFPrkIseLDrCanlvlkYgpeLDaDHPGFkDqvYRqRRKyfAdIA
pWFP kI + D +an++l+Yg+eLDaDHPGFkD YR RRK fAdIA
K08F8.4 119 PWFPQKINDIDQFANRILSYGAELDADHPGFKDMTYRERRKFFADIA 165
fnYKhGdPIPrVeYteEEikTWgtVFktLkkLYPTHACrEYleaFpLLek
fn KhGd IP + Yt+EEi+TW+tV+ +L+ YP+ AC E++ +FpLL+
K08F8.4 166 FNFKHGDKIPTITYTDEEIATWRTVYNELTVMYPKNACQEFNYIFPLLQQ 215
yCGfrEdnIPQLEDVSnFLkerTGFsLRPVAGLLSaRDFLAgLAFRVFhc
+CGf d+IPQL+DVS+FLk++TG ++RPVAGLLS+RDFLAgLAFRVFh+
K08F8.4 216 NCGFGPDRIPQLQDVSDFLKDCTGYTIRPVAGLLSSRDFLAGLAFRVFHS 265
TQYiRHaSsPmyTPEPDvCHELLGHVPLLADpsFAQFSQEIGLASLGAsD
TQYiRH S P yTPEPD+CHELLGHVPL+AD FAQFSQEIGLASLGA+D
K08F8.4 266 TQYIRHHSAPKYTPEPDICHELLGHVPLFADVEFAQFSQEIGLASLGAPD 315
EeIEKLaTiYWFTVEFGLCKQnGqiKAYGAGLLSSYGELlHaLSdkpelr
+ IEKLaT+YWFT+EFG+C Q+G+ KAYGAGLLSS+GEL++aLSdkpe+
K08F8.4 316 DVIEKLATLYWFTIEFGICQQDGEKKAYGAGLLSSFGELQYALSDKPEVV 365
aFePeaTAvQpYqitefQPvYyVaESFeDAKeKlRnfastIkRPFsVrYn
+F+P++ +v++Y+ite+QP Y+ aESF AK+Kl ++a+tI RPF +rYn
K08F8.4 366 DFDPAVCCVTKYPITEYQPKYFLAESFASAKNKLKSWAATINRPFQIRYN 415
PYTqsIeVLDstqqiehlldsinsElqiLtnAlakis<-*
+YTq++e+LD + +++ l+ i+s++ +L +Al k+
K08F8.4 416 AYTQRVEILDKVAALQRLARDIRSDISTLEEALGKVN 452