Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm3/seq/K11D2.2
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Query:  K11D2.2  CE12120   Human PHP32 protein like status:Confirmed SW:O45686 protein_id:CAB05556.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
CBAH     Linear amide C-N hydrolases, choloylglycine     78.1    4.5e-22   2

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
CBAH       1/2     140   294 ..     1   181 [.    58.5  2.5e-16
CBAH       2/2     312   381 ..   214   328 ..    21.1  2.4e-05

Alignments of top-scoring domains:
CBAH: domain 1 of 2, from 140 to 294: score 58.5, E = 2.5e-16
                   *->CTsltledkkgkllfGRNMDfgvFLGWnislgeeVI...itPrnykl
                      CTs ++ dk+g++ ++RN+Dfg F+GW+  l  + I++++    +++
     K11D2.2   140    CTSVIAQDKDGHVFHARNLDFGLFMGWDPVLHDWQIsqkLRKMIINV 186

                   vfLeklgkllvtkyNPaQwtsKygsvvTAvvGYMGtlvdsyP.lFaDglN
                   +   k+gkll  +                + GY+G+  + +P+ F+++
     K11D2.2   187 NW-LKDGKLLYKSN--------------NFAGYIGIYNGLKPnAFSLTAD 221

                   EkGLgiAGLYfGipgyaeyskepkedkvnIqpgelirwV....LeNftSV
                    + +   G+Y+Gi+ ++++    +        g +++w+ +++Le  t++
     K11D2.2   222 DR-FQLVGGYYGILKWVFGLEA-D--------GKWMSWLaretLETKTTY 261

                   eEVKekLtklniVnealdilggkaPLHWiisDkSGesiVItR<-*
                    ++Ke L ++  + ++++ilgg          k +e+++I R
     K11D2.2   262 LDAKEHLMNTPMLSPVYFILGGS---------KKDEGCIIAR    294

CBAH: domain 2 of 2, from 312 to 381: score 21.1, E = 2.4e-05
                   *->wHlvqtNLdqYtGlrpnqpqelfmgdldLtafGqGtGglGLPGDftP
                      w+l  tN+dq t       ++l ++d+d                 tP
     K11D2.2   312    WYLLETNYDQGT-------EDLYLDDRD-----------------TP 334

                   asRFVRAAYlKknlekaktEsesvatfFhILsnvaipKGaVlneeGkley
                               ++ k ++++ +++++F++Ls+ +      ln     ++
     K11D2.2   335 G---------FRCMDKLTQKNVGFEGIFNVLSSRT-----NLN-----KL 365

                   TvYTscmdltkgqYYFet<-*
                   T YT +m++++ +  Fet
     K11D2.2   366 TTYTVLMSVETSR--FET    381



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