Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm4/seq/M04F3.3
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Query:  M04F3.3  CE12416   protein kinase status:Partially_confirmed TR:Q95Y99 protein_id:AAK71382.1

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
pkinase      Protein kinase domain                       25.4      6e-06   1
glutaredoxin Glutaredoxin                                 7.6       0.84   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
pkinase        1/1      25   160 ..    64   187 ..    25.4    6e-06
glutaredoxin   1/1     253   290 ..    19    63 ..     7.6     0.84

Alignments of top-scoring domains:
pkinase: domain 1 of 1, from 25 to 160: score 25.4, E = 6e-06
                   *->igvfed..tddhlylvmEymegGdLfdy..lrrnggplsekeakkia
                      i+++ d+  +d+ y+vm +++  dL ++ +l++n+  ++ + +++++
     M04F3.3    25    IHIYDDgiYKDYRYIVMTLCGP-DLQKIaeLMNNN--FNQDTIIRVC 68

                   lQilrGleYLHsngivHRDLKpeNILlden..dgtvKiaDFGLArlle..
                     +l +++ +H+   +HRDLKp N+ +d n++  +v + D G+Ar++ ++
     M04F3.3    69 IRTLLAIKTMHEYTYIHRDLKPCNFAVDFNpnSLHVYLFDYGMARKYAtk 118

                   .........sssklttfvGTpwYmmAPEvilegrgysskvDvWS<-*
                   +++++ + ++  +  +f GT +Y+ +     ++++ s+  D WS
     M04F3.3   119 dsgnkwqlrRPRNPAQFRGTVRYC-SLNM-HKRKELSRVDDLWS    160

glutaredoxin: domain 1 of 1, from 253 to 290: score 7.6, E = 0.84
                   *->ellkklkvergdfevveidgeddgseiqdalakltkekeGqrTVP<-
                      +l+ +l++   +++  e++++dd+s+iq++l+ +     G+ +VP
     M04F3.3   253    ALVAELGE---TARPKELSRMDDESTIQKYLLASF----GRAGVP   290

                   *

     M04F3.3     -   -



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