Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/M110.5b
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: M110.5b CE23877 status:Predicted TR:Q9U3A6 protein_id:CAB54271.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
PID Phosphotyrosine interaction domain (PTB/ 77.4 1.2e-20 1
Fic Fic protein family 5.4 5.3 1
PTPS 6-pyruvoyl tetrahydropterin synthase 1.8 7.5 1
2-Hacid_DH_C D-isomer specific 2-hydroxyacid dehydrog 0.4 8.5 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
2-Hacid_DH_C 1/1 49 63 .. 94 108 .. 0.4 8.5
PTPS 1/1 105 113 .. 136 144 .] 1.8 7.5
PID 1/1 110 234 .. 1 164 [] 77.4 1.2e-20
Fic 1/1 220 279 .. 1 51 [. 5.4 5.3
Alignments of top-scoring domains:
2-Hacid_DH_C: domain 1 of 1, from 49 to 63: score 0.4, E = 8.5
*->frvdsLDeLlaqsDv<-*
f+++sL+++ ++sD+
M110.5b 49 FFYCSLETMAQKSDI 63
PTPS: domain 1 of 1, from 105 to 113: score 1.8, E = 7.5
*->kNIviYrGe<-*
+N+++Y+G
M110.5b 105 NNGISYKGK 113
PID: domain 1 of 1, from 110 to 234: score 77.4, E = 1.2e-20
*->FeVkYLGsveVpkemrapskstRmqvareairrlreavKkpkakkik
++ k++G +V+k+ +++a++ +++ +++
M110.5b 110 YKGKLIGEQDVDKA------------RGDAMCAEAMR------TAKS 138
rskgssgerqagtkidLsistdglklldekteaekevihehplrkISFiA
++k+ ++t+i+L+i +dg+k+ldek+ ++v+h++p+ +ISFiA
M110.5b 139 IIKAAG---AHKTRITLQINIDGIKVLDEKS---GAVLHNFPVSRISFIA 182
vggDpdVdlraFayvrstddsliaadgatsrfaCHvFecekgkqlAedia
D+ d raF++ + ++++ + F +k++q+A + +
M110.5b 183 R--DSS-DARAFGL--------VYGEPGGK----YKFYGIKTAQAADQAV 217
eavgqAFevaYqeflra<-*
+a+++ F+v+++ +++
M110.5b 218 LAIRDMFQVVFEMKKKQ 234
Fic: domain 1 of 1, from 220 to 279: score 5.4, E = 5.3
*->llelHrilfeddydwaGqfRttqvakv.........gnfvfpppeav
++++ + fe+ ++ + q+++ q+ +++ + +++++g++ ++ +++
M110.5b 220 IRDMFQVVFEMKKKQIEQVKQQQIQDGgaeisskkeGGVAVADLLDL 266
ealldrlfqwlnn<-*
e +l+ ++ ++
M110.5b 267 ESELQQIERGVQQ 279