Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm4/seq/M110.5a
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Query:  M110.5a  CE23876   disabled-like protein status:Partially_confirmed TR:Q9U3A6

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
PID          Phosphotyrosine interaction domain (PTB/    77.4    1.2e-20   1
Fic          Fic protein family                           5.4        5.3   1
PTPS         6-pyruvoyl tetrahydropterin synthase         1.8        7.5   1
2-Hacid_DH_C D-isomer specific 2-hydroxyacid dehydrog     0.4        8.5   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
2-Hacid_DH_C   1/1      49    63 ..    94   108 ..     0.4      8.5
PTPS           1/1     105   113 ..   136   144 .]     1.8      7.5
PID            1/1     110   234 ..     1   164 []    77.4  1.2e-20
Fic            1/1     220   279 ..     1    51 [.     5.4      5.3

Alignments of top-scoring domains:
2-Hacid_DH_C: domain 1 of 1, from 49 to 63: score 0.4, E = 8.5
                   *->frvdsLDeLlaqsDv<-*
                      f+++sL+++ ++sD+
     M110.5a    49    FFYCSLETMAQKSDI    63

PTPS: domain 1 of 1, from 105 to 113: score 1.8, E = 7.5
                   *->kNIviYrGe<-*
                      +N+++Y+G
     M110.5a   105    NNGISYKGK    113

PID: domain 1 of 1, from 110 to 234: score 77.4, E = 1.2e-20
                   *->FeVkYLGsveVpkemrapskstRmqvareairrlreavKkpkakkik
                      ++ k++G  +V+k+            +++a++  +++       +++
     M110.5a   110    YKGKLIGEQDVDKA------------RGDAMCAEAMR------TAKS 138

                   rskgssgerqagtkidLsistdglklldekteaekevihehplrkISFiA
                   ++k+      ++t+i+L+i +dg+k+ldek+   ++v+h++p+ +ISFiA
     M110.5a   139 IIKAAG---AHKTRITLQINIDGIKVLDEKS---GAVLHNFPVSRISFIA 182

                   vggDpdVdlraFayvrstddsliaadgatsrfaCHvFecekgkqlAedia
                      D+  d raF++        + ++++      + F  +k++q+A + +
     M110.5a   183 R--DSS-DARAFGL--------VYGEPGGK----YKFYGIKTAQAADQAV 217

                   eavgqAFevaYqeflra<-*
                   +a+++ F+v+++ +++
     M110.5a   218 LAIRDMFQVVFEMKKKQ    234

Fic: domain 1 of 1, from 220 to 279: score 5.4, E = 5.3
                   *->llelHrilfeddydwaGqfRttqvakv.........gnfvfpppeav
                      ++++ +  fe+ ++ + q+++ q+ +++ + +++++g++  ++ +++
     M110.5a   220    IRDMFQVVFEMKKKQIEQVKQQQIQDGgaeisskkeGGVAVADLLDL 266

                   ealldrlfqwlnn<-*
                   e +l+ ++   ++
     M110.5a   267 ESELQQIERGVQQ    279



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