Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm4/seq/R01E6.4
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Query:  R01E6.4  CE29334  locus:acr-12 acetylcholine receptor protein status:Confirmed TR:Q9GQU9 protein_id:CAA92184.2

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N
--------       -----------                              -----    ------- ---
Neur_chan_LBD  Neurotransmitter-gated ion-channel lig   340.3    2.1e-98   1
Neur_chan_memb Neurotransmitter-gated ion-channel tra   153.0    2.9e-44   2

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
Neur_chan_LBD    1/1      38   264 ..     1   246 []   340.3  2.1e-98
Neur_chan_memb   1/2     271   381 ..     1   117 [.   111.4  5.3e-32
Neur_chan_memb   2/2     490   539 ..   229   291 .]    40.6    4e-11

Alignments of top-scoring domains:
Neur_chan_LBD: domain 1 of 1, from 38 to 264: score 340.3, E = 2.1e-98
                   *->etrLlddLlentvsgYdkrvRPv.nggdvPpvtVsvgltlqqiisVd
                      e++L++dLl +    Y+k  RPv+n +d   +tV vg +l  ii+Vd
     R01E6.4    38    ESQLYEDLLFD----YNKVPRPVkNSSD-I-LTVDVGASLIRIIDVD 78

                   EknqdlttnvwlrqgqWtDpRLaWnpsdplddeddyggikslrlpsddeh
                   Eknq+lttn+wl++ +W+D +L+W p+        ygg k+l++psd
     R01E6.4    79 EKNQVLTTNLWLEM-KWNDAKLTWTPEK-------YGGLKTLHIPSD--- 117

                   dmldkIWlPDiflyNqttskadgnhdvttpntnvrvypglkdGtVlwspp
                       +IW+PD++lyN    +a+g+ d+t   t ++v+     G+V+w pp
     R01E6.4   118 ----FIWTPDLVLYN----NAAGDPDIT-ILTDALVTF---EGNVYWQPP 155

                   aiykssCpmdltyFPFDqQnCslkFgSwtYngdevdlqwkdd........
                   aiyks+Cp+d+t+FP+D+Q C +kFg wtY+g  vdl+  ++++  + ++
     R01E6.4   156 AIYKSFCPIDVTWFPYDSQKCEMKFGTWTYTGRYVDLKQLPQeevvtitk 205

                   ........leeidLpdFtengeWdlldvpakrnekpygcyselsgagLnk
                   ++++ +  ++++dL+ F+ + eWdll++++ r++  y +++++++
     R01E6.4   206 ddndvefmQQGMDLSFFYRSAEWDLLSLTSERHSVLYASCCGPEK----- 250

                   lvYpditfyfvlrRkp<-*
                     Y+dit+yf lrRk+
     R01E6.4   251 --YVDITYYFGLRRKT    264

Neur_chan_memb: domain 1 of 2, from 271 to 381: score 111.4, E = 5.3e-32
                   *->liiPCvLIsfLswLvFyLPsDaGPeKvtLgIsvLLtlTvFlllirei
                      li+PC LIs+L+  vFyL       K+t++Is+L tlTvF+l++ +
     R01E6.4   271    LILPCFLISILTTFVFYLSD----HKITFSISILVTLTVFFLVLIDL 313

                   lPkTSlvvPLigkYllFtMfvvtasieyavvvlnvhhRsPkstHkmpewv
                   +P+TSlv+P+ g Yl+ tM++v++s +++v+  n+ +Rs  s Hkm++w+
     R01E6.4   314 MPPTSLVIPMFGRYLITTMILVALSTVVSVITVNFRFRSG-SAHKMSPWI 362

                   rklfLerklPrllfmkrpne<-*
                   r +fL ++lP++l+m+rp++
     R01E6.4   363 RAVFL-KFLPKILLMSRPEK    381

Neur_chan_memb: domain 2 of 2, from 490 to 539: score 40.6, E = 4e-11
                   *->vegvsrrfIaehkppkeavkawlrskdeddsvkedWkyvamvIDRlf
                      ++ v  rfIaeh          +r    + ++ +dW +vamv+DRlf
     R01E6.4   490    LNQV--RFIAEH----------FRHNELEGEISDDWTFVAMVLDRLF 524

                   lwiFpivfvlGTlgyf<-*
                   l+iF ++ v GT+++
     R01E6.4   525 LIIFSVLNV-GTVFII    539



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