Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/R01E6.4
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Query: R01E6.4 CE29334 locus:acr-12 acetylcholine receptor protein status:Confirmed TR:Q9GQU9 protein_id:CAA92184.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Neur_chan_LBD Neurotransmitter-gated ion-channel lig 340.3 2.1e-98 1
Neur_chan_memb Neurotransmitter-gated ion-channel tra 153.0 2.9e-44 2
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Neur_chan_LBD 1/1 38 264 .. 1 246 [] 340.3 2.1e-98
Neur_chan_memb 1/2 271 381 .. 1 117 [. 111.4 5.3e-32
Neur_chan_memb 2/2 490 539 .. 229 291 .] 40.6 4e-11
Alignments of top-scoring domains:
Neur_chan_LBD: domain 1 of 1, from 38 to 264: score 340.3, E = 2.1e-98
*->etrLlddLlentvsgYdkrvRPv.nggdvPpvtVsvgltlqqiisVd
e++L++dLl + Y+k RPv+n +d +tV vg +l ii+Vd
R01E6.4 38 ESQLYEDLLFD----YNKVPRPVkNSSD-I-LTVDVGASLIRIIDVD 78
EknqdlttnvwlrqgqWtDpRLaWnpsdplddeddyggikslrlpsddeh
Eknq+lttn+wl++ +W+D +L+W p+ ygg k+l++psd
R01E6.4 79 EKNQVLTTNLWLEM-KWNDAKLTWTPEK-------YGGLKTLHIPSD--- 117
dmldkIWlPDiflyNqttskadgnhdvttpntnvrvypglkdGtVlwspp
+IW+PD++lyN +a+g+ d+t t ++v+ G+V+w pp
R01E6.4 118 ----FIWTPDLVLYN----NAAGDPDIT-ILTDALVTF---EGNVYWQPP 155
aiykssCpmdltyFPFDqQnCslkFgSwtYngdevdlqwkdd........
aiyks+Cp+d+t+FP+D+Q C +kFg wtY+g vdl+ ++++ + ++
R01E6.4 156 AIYKSFCPIDVTWFPYDSQKCEMKFGTWTYTGRYVDLKQLPQeevvtitk 205
........leeidLpdFtengeWdlldvpakrnekpygcyselsgagLnk
++++ + ++++dL+ F+ + eWdll++++ r++ y +++++++
R01E6.4 206 ddndvefmQQGMDLSFFYRSAEWDLLSLTSERHSVLYASCCGPEK----- 250
lvYpditfyfvlrRkp<-*
Y+dit+yf lrRk+
R01E6.4 251 --YVDITYYFGLRRKT 264
Neur_chan_memb: domain 1 of 2, from 271 to 381: score 111.4, E = 5.3e-32
*->liiPCvLIsfLswLvFyLPsDaGPeKvtLgIsvLLtlTvFlllirei
li+PC LIs+L+ vFyL K+t++Is+L tlTvF+l++ +
R01E6.4 271 LILPCFLISILTTFVFYLSD----HKITFSISILVTLTVFFLVLIDL 313
lPkTSlvvPLigkYllFtMfvvtasieyavvvlnvhhRsPkstHkmpewv
+P+TSlv+P+ g Yl+ tM++v++s +++v+ n+ +Rs s Hkm++w+
R01E6.4 314 MPPTSLVIPMFGRYLITTMILVALSTVVSVITVNFRFRSG-SAHKMSPWI 362
rklfLerklPrllfmkrpne<-*
r +fL ++lP++l+m+rp++
R01E6.4 363 RAVFL-KFLPKILLMSRPEK 381
Neur_chan_memb: domain 2 of 2, from 490 to 539: score 40.6, E = 4e-11
*->vegvsrrfIaehkppkeavkawlrskdeddsvkedWkyvamvIDRlf
++ v rfIaeh +r + ++ +dW +vamv+DRlf
R01E6.4 490 LNQV--RFIAEH----------FRHNELEGEISDDWTFVAMVLDRLF 524
lwiFpivfvlGTlgyf<-*
l+iF ++ v GT+++
R01E6.4 525 LIIFSVLNV-GTVFII 539