Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/R02C2.1
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: R02C2.1 CE21086 protein kinase status:Partially_confirmed TR:O44547 protein_id:AAD32717.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
pkinase Protein kinase domain 483.4 1.8e-141 2
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
pkinase 1/2 18 280 .. 1 294 [] 231.9 9e-66
pkinase 2/2 343 612 .. 1 294 [] 252.6 5.5e-72
Alignments of top-scoring domains:
pkinase: domain 1 of 2, from 18 to 280: score 231.9, E = 9e-66
*->yelleklGeGsfGkVykakhkdkt.gkiVAvKilkk.ekesikekrf
ye++e lGeGsf++V ++ + +t++k +A+K+++ +k + + +
R02C2.1 18 YEFIENLGEGSFAEVVLVAKV-GTpNKMFAMKEISIvGKDECFMESI 63
lrEiqilkrLs...HpNIvrligvfedtddhlylvmEymegGdLfdylrr
rE +i krLs+++H N + l+++ + ++++ l++ y++gGdLf+ + +
R02C2.1 64 KRECSIQKRLSksrHLNMIHLFEIRT-NPENYQLILSYADGGDLFEKINQ 112
nggplsekeakkialQilrGleYLHsngivHRDLKpeNILldendgtvKi
+g l+ +ea ++++Q+ Gl ++H++g+ HRD+KpeN+Ll++ g +Ki
R02C2.1 113 HG-GLGSDEAHRYFKQLIDGLRFIHEEGVTHRDIKPENLLLTKS-GILKI 160
aDFGLArlle...sssklttfvGTpwYmmAPEvileg.rgysskvDvWSl
aDFG+A+ + ++ ++l+ ++G+p+Y+ APEv l g ++ +++vD+WS+
R02C2.1 161 ADFGFATMHRfngAEQMLNAYCGSPPYI-APEV-LTGiDYRGPAVDIWSA 208
GviLyElltggplfpgadlpaftggdevdqliifvlklPfsdelpktrid
Gv+L+ + g P+++ + d
R02C2.1 209 GVVLIAMIAG--------------------------AVPWEQ---ADHFD 229
pleelfriikrpglrlplpsncSeelkdLlkkcLnkDPskRpGsatakei
+++ ++ +r ++r +s+ S +++Ll+k+L + ++ R t+ i
R02C2.1 230 IFQSRYCSFRR-NGRKGAWSRMSQQVISLLRKIL-LQAELRA---TISMI 274
lnhpwf<-*
++pwf
R02C2.1 275 EEDPWF 280
pkinase: domain 2 of 2, from 343 to 612: score 252.6, E = 5.5e-72
*->yelleklGeGsfGkVykakhkdktgkiVAvKilkk.ekesikekrfl
y+++e+l +GsfG+V ++++ + +VAvK++ +++k++++ + ++
R02C2.1 343 YKVVEHLCKGSFGQVHLCELTRNPSVKVAVKEVAVsGKSRKNLTAVQ 389
rEiqilkrLs...HpNIvrligvfedtddhlylvmEymegGdLfdylrrn
E +i++rLs+ +H+N++++ + e t++ + lvmEy++gGdLfd l+++
R02C2.1 390 KEYKIHRRLSkigHENVIQMMKMIE-TPKFYSLVMEYADGGDLFDELKEQ 438
ggplsekeakkialQilrGleYLHsngivHRDLKpeNILlden.....dg
++s k+a ++++Q+ +Gl+++H++givHRD+K eN+Ll+ ++++++g
R02C2.1 439 E-KFSRKDAHSYFKQLIKGLKFIHEQGIVHRDIKLENLLLVYSeseddPG 487
tvKiaDFGLArlle...sssklttfvGTpwYmmAPEvilegrgysskvDv
t+Ki+DFGLA+++++++ +l+ +G+ +Y APEv+ +++ +++vD+
R02C2.1 488 TLKITDFGLATKYRkdgEEIMLSEDCGSKPYA-APEVCTGNDYRGPPVDI 536
WSlGviLyElltggplfpgadlpaftggdevdqliifvlklPfsdelpkt
WS+Gv+L +l g + ++ +
R02C2.1 537 WSAGVVLMTMLVG--------------------------EHSWK----VA 556
ridpleelfriikrpglrlplpsncSeelkdLlkkcLnkDPskRpGsata
++++ +++ + i+ ++++ l+ +S + Ll+k+L+ +P+kR t+
R02C2.1 557 NKEKDAAYSNWINAKDEKANLWNVISGPTTALLRKLLHANPEKRA---TM 603
keilnhpwf<-*
i ++pwf
R02C2.1 604 AKIEADPWF 612