Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/R03D7.1
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Query: R03D7.1 CE01609 5-methyltetrahydrofolate-homocysteine methyltransferase status:Partially_confirmed SW:Q09582 protein_id:CAA86855.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Met_synt_B12 Vitamin B12 dependent methionine synth 677.1 8.6e-200 1
S-methyl_trans Homocysteine S-methyltransferase 570.9 8.3e-168 1
Pterin_bind Pterin binding enzyme 323.1 3.1e-93 1
B12-binding_2 B12 binding domain 170.3 3.3e-47 1
B12-binding B12 binding domain 104.9 2e-28 1
Aldolase_II Class II Aldolase and Adducin N-termin 6.9 0.62 1
PMSR Peptide methionine sulfoxide reductase 4.8 4.4 1
Polyoma_coat Polyomavirus coat protein 1.9 8 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Polyoma_coat 1/1 170 183 .. 1 14 [. 1.9 8
Aldolase_II 1/1 291 311 .. 1 21 [. 6.9 0.62
S-methyl_trans 1/1 18 329 .. 1 344 [] 570.9 8.3e-168
Pterin_bind 1/1 360 608 .. 1 287 [] 323.1 3.1e-93
B12-binding_2 1/1 653 747 .. 1 92 [] 170.3 3.3e-47
B12-binding 1/1 763 862 .. 1 117 [. 104.9 2e-28
PMSR 1/1 1099 1112 .. 151 164 .] 4.8 4.4
Met_synt_B12 1/1 922 1214 .. 1 337 [] 677.1 8.6e-200
Alignments of top-scoring domains:
Polyoma_coat: domain 1 of 1, from 170 to 183: score 1.9, E = 8
*->LLiKGGvEVLdVrT<-*
+Li GGv VL V T
R03D7.1 170 SLIQGGVDVLLVET 183
Aldolase_II: domain 1 of 1, from 291 to 311: score 6.9, E = 0.62
*->qelaaacrllalyGlvtgtaG<-*
+e+a++ r++a++Glv ++G
R03D7.1 291 EEMADVLREFARDGLVNIIGG 311
S-methyl_trans: domain 1 of 1, from 18 to 329: score 570.9, E = 8.3e-168
*->vlvlDGgmGTeLqrrglnladplwsafkDhpfplegcneelsitkPe
++++DG+mGT++qr++++++d+++++ kDh++pl+g+n++lsit+P+
R03D7.1 18 IMIIDGAMGTMIQREYMEEEDFRGEILKDHDKPLKGNNDLLSITRPD 64
vireiHkaYleAGAdiieTnTyqatiDkPTWRAQpigfadygledlelre
+i++iHk YleAGAd++eTnT+++t +i++ady++e+l+ +e
R03D7.1 65 IIYKIHKLYLEAGADFVETNTFSGT---------TIAQADYRCEHLV-HE 104
lnrraveiARaaadeygnlgenstgdkprlVaGsiGPygatlsdSPGsey
+n++++ +AR+a+d++g ++tg++ r+V+G iGP+++tls+SP++e
R03D7.1 105 INYQSALVARRACDDVG----AATGRR-RYVCGAIGPTNRTLSISPSVEK 149
pgyygvsfenielkkayrpqlegLldgGivDlLllETipdlleakAavra
p++++v+f+ el+kay +q+++L++gG vD+Ll+ET++d ++akAa++a
R03D7.1 150 PDFRNVTFQ--ELVKAYGDQARSLIQGG-VDVLLVETVFDSANAKAALFA 196
veevfeapawislpvkdsgtivdgtgltlsgatieallnsvkqaeivavG
++++fe+++++++pv+ sgtivd++g+tlsg+t+ea+l s+kq++++avG
R03D7.1 197 IRTLFEDEGVPEMPVFLSGTIVDMSGRTLSGQTGEAFLVSTKQGKPMAVG 246
vNCalgpdimdellellsltphadkplsvyPNRRsGepydagkQrkeyde
+NCalg+++m+++++++s+ ++d ++++yPN +G+p++ g +yde
R03D7.1 247 LNCALGAKDMRQFVDNMSK--WSDSFIICYPN--AGLPNALG----GYDE 288
tpdelaeSygqslkefvasGaNLVriIGGCCGTtPdHIreIaeavdk<-*
tp+e+a+ +l+ef+++G+ V+iIGGCCGTtPdHI+++++av++
R03D7.1 289 TPEEMAD----VLREFARDGL--VNIIGGCCGTTPDHINAMYKAVQG 329
Pterin_bind: domain 1 of 1, from 360 to 608: score 323.1, E = 3.1e-93
*->ilNvTpDSFsDGGkffr.liqaesldkAlarAkemveeGAdIIDiGg
++N++++++++G+++f++li++e++d+A++ A+ +v++GA+I+D+++
R03D7.1 360 FVNIGERCNVAGSRRFCnLIKNENYDTAIDVARVQVDSGAQILDVNM 406
eStrPgaepVsveeEleRvvPVlealrdelnkvsdvpISvDTfkaevaea
+ + ++ ++++++ +++ ++d v+++p+++D++ +v+ a
R03D7.1 407 DDGLL-----DGPYAMSKFLRLISSEPD----VAKIPVCIDSSDFDVIIA 447
ALkvlaGadiiNDvsggngEErdpemaplaaeydgapvVlMHmrgdpqak
+L+ ++G++++N++s+++gEE++ e a+ +++y ga+vV+M++++++qa
R03D7.1 448 GLESTQGKCVVNSISLKEGEEKFKERARIIKRY-GAAVVVMAFDEQGQAA 496
trqakTmqenpddYeeLtpdvveevlefleerleaLaeeaGikpperIil
++ + + e++e+ +++L+ee+G+ +p++Ii+
R03D7.1 497 ET--------------------DPKFEICERSYRILTEEVGF-NPNDIIF 525
DPGiGFiaTGigKtpehnlelLraldelkrnLlgyPlLlGvSRKsFlgrl
D +i++iaTG++++ ++++ +++a + +++nL+g+++ +GvS++sF +r+
R03D7.1 526 DANILTIATGMEEHSNYGMYFIEAARMIRENLPGAHVSGGVSNISFSFRG 575
lggiNallapkdRdagtlAflalAiqkGadaAIVRVHdvaa<-*
+ + R+a++++fl +Ai++G+d++IV+++ +++
R03D7.1 576 M--------EAIREAMHSVFLFYAIKAGMDMGIVNAGALPV 608
B12-binding_2: domain 1 of 1, from 653 to 747: score 170.3, E = 3.3e-47
*->eaemakeevlerlaeAivdgeeagvvelleeAle...agkdPldiIe
++e++++ v+erl+ A+v+g++++vv+++eeA++++ ++++Pl++Ie
R03D7.1 653 TDEWRSLTVEERLKFALVKGVDQFVVADTEEARQntaKYPRPLNVIE 699
kgLmdGMkvVGelFgeGemFLPqVlmsAeaMkkgVevLkPlmekdkse<-
++LmdGM vVGelFg+G+mFLPqV++sA++Mkk+V++L P+me ++++
R03D7.1 700 RPLMDGMAVVGELFGAGKMFLPQVIKSARVMKKAVAHLLPFMEIERQA 747
*
R03D7.1 - -
B12-binding: domain 1 of 1, from 763 to 862: score 104.9, E = 2e-28
*->grvvlakvggdgHdiGanvvaaaLrdaGiafevrVvdlGarplhldv
g+vv+a+v+gd+HdiG+n+v+ +L ++ f+ VvdlG+ +
R03D7.1 763 GTVVIATVKGDVHDIGKNIVSVVLGCNN--FK--VVDLGV-----MT 800
ppediveaakeekdpDkvvvglgSalsgahlelvkelaelLkeagknirp
p e+i++aa+ee ++D +gl S+l++ +l+++ ++a+++ + g+
R03D7.1 801 PCENIIKAAIEE-KAD--FIGL-SGLITPSLDEMVYVAKEMNRVGL---- 842
dvpvvvGGaavhptfdpael<-*
++p+++GGa + t+ + ++
R03D7.1 843 NIPLLIGGATTSKTHTAVKI 862
PMSR: domain 1 of 1, from 1099 to 1112: score 4.8, E = 4.4
*->LkKnPnGYchidhl<-*
L+Kn+++Y++i++
R03D7.1 1099 LEKNHDDYASIMVK 1112
Met_synt_B12: domain 1 of 1, from 922 to 1214: score 677.1, E = 8.6e-200
*->LeeARekgfsgdwpsdyepPaPpflGvrvvegsDLdlaelrpyiDwk
L+++Rek+f++dw+ ++++++P+f+G+r+++++D l+el+pyiDwk
R03D7.1 922 LNKTREKKFKIDWD-KFTAVKPSFVGRREYQNFD--LNELIPYIDWK 965
PfFrGqWgLrRKGFPGkYprrgypkifydplvGeEaRkvfkdAqdmLskl
PfF+ +W+Lr GkYp+r+ypkif+d++vG+Ea+kvf+dAq++L+kl
R03D7.1 966 PFFD-VWQLR-----GKYPNRSYPKIFDDADVGAEAKKVFDDAQTWLKKL 1009
iseklLrarGVvGlfPAqsDDivLDDAAmGRGeGdDilvyapaLVSQNNk
i+ek+L+a++Vv+++PA+s eGdD++vy
R03D7.1 1010 IDEKILVANAVVSFLPAAS-------------EGDDMHVY---------- 1036
adppdaeaiatfygLRQQsGRgkaktepnlCLaDFiaplksATEggirDv
dp+++++++tfygLRQQsGR+ +++p++CL+DFi+plk+ g+++D+
R03D7.1 1037 -DPETGNKLDTFYGLRQQSGRE--HDQPHFCLSDFIKPLKN---GVPDDY 1080
lGlFAVTvGegaeelaqaleasgdDydyimVkAlaDrLAEAlAEYLHkRv
lGlFA+T+G+gaee++++le+++dDy++imVkAlaDrLAEA+AEYLHk+v
R03D7.1 1081 LGLFACTAGLGAEEYCKTLEKNHDDYASIMVKALADRLAEAYAEYLHKEV 1130
RtelWGYaeRTmShedldnidllfeqGYqGiRpApGYPAcPDhtEKatlw
Rt+lWGY++ +edl+++dll+++ YqGiRpA+GYP++PDhtEK+tlw
R03D7.1 1131 RTTLWGYST----NEDLTESDLLSIK-YQGIRPACGYPSQPDHTEKRTLW 1175
eLLevEritGvkLTEslAmwPaaSVSGlyfhHPaAkYFaV<-*
+LLe+E++ G++LTE+lAm+PaaSVSGlyf++P+++YFaV
R03D7.1 1176 KLLEAEKN-GIGLTEHLAMLPAASVSGLYFANPQSEYFAV 1214