Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm4/seq/R03G8.3
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Query:  R03G8.3  CE03527    status:Partially_confirmed TR:Q21672 protein_id:CAA93678.1

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N
--------      -----------                               -----    ------- ---
DUF229        Protein of unknown function (DUF229)      316.1    4.1e-91   3
PB1           PB1 domain                                  6.0        3.4   1
DUF701        Putative zinc binding domain (DUF701)       5.2        8.8   1
Cytomegalo_gL Cytomegalovirus glycoprotein L              5.1        1.6   1
Sulfatase     Sulfatase                                   2.9        2.1   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
PB1             1/1      56    91 ..    50    85 .]     6.0      3.4
DUF229          1/3     193   397 ..     1   254 [.   143.4  6.8e-40
DUF701          1/1     444   460 ..    46    64 .]     5.2      8.8
Cytomegalo_gL   1/1     483   499 ..   267   285 .]     5.1      1.6
Sulfatase       1/1     501   514 ..   320   333 ..     2.9      2.1
DUF229          2/3     444   668 ..   316   561 .]   167.5  1.1e-46
DUF229          3/3     714   746 ..   530   561 .]    10.1    0.038

Alignments of top-scoring domains:
PB1: domain 1 of 1, from 56 to 91: score 6.0, E = 3.4
                   *->dlVsissDeDLeeaieeyrsllsegsktlrlfvfpa<-*
                      +l+ i+s++DL+    +++++ls+++  ++lfvfp+
     R03G8.3    56    SLLRINSQDDLDSHEVFANRALSQRTLMFKLFVFPT    91

DUF229: domain 1 of 3, from 193 to 397: score 143.4, E = 6.8e-40
                   *->sifkpnpylkCsketllttktfnitfgylrlnidaelalarlnvesl
                       +++ np ++C+k++ ++t++ n++ +  + +++
     R03G8.3   193    LNMEVNPISNCNKSREPLTFL-NNGSWGVVNKKT------------- 225

                   enleCyykreikRkrdsaniygysklfklppkltqsvkvpvgiiegevef
                    +l C++ r+++Rk ++ n +g+++++++          p++     +e+
     R03G8.3   226 -KLICRA-RCHTRKSERYNVIGNWTYTPG----------PIN-----CEV 258

                   irteCwsdfgkiyrkflqkDvfeflhdeerlriipksgdkrvktekstpk
                   ++ +C ++ +  y         +flh+    ++i +++   +++ ++ +
     R03G8.3   259 VEAVCADGKKDVY---------GFLHT----QVIATPP---KQPTVKVS- 291

                   esdkpSVlilGlDSlSrmnfrRsMPrTvkflesnlgwvefqGYNKVGDNT
                   e + ++V ++ lDSlS ++++Rs+ rT ++++++++ v f++ NKVGDN+
     R03G8.3   292 ELKNYDVTVIMLDSLSFTQAKRSLLRTISYMTNHMDAVLFPYINKVGDNS 341

                   fpNLlplLtGkllEavkklidsegeaeancdlppskegclDkcpfIWKdF
                   +pN+ +l++Gk+lE++++  ++e ++  +++  + ++++ D+ + ++K++
     R03G8.3   342 RPNGAALWFGKSLEKLDRSLFEEENVPVDWSHAYMCHVYKDNETSLFKEY 391

                   kdaYGYa<-*
                   ++  GY+
     R03G8.3   392 QNY-GYK    397

DUF701: domain 1 of 1, from 444 to 460: score 5.2, E = 8.8
                   *->CRvgesfqtninpLsepiD<-*
                      C   e+++t   +Ls+ i+
     R03G8.3   444    C--REDHHTLLDYLSQFIN    460

Cytomegalo_gL: domain 1 of 1, from 483 to 499: score 5.1, E = 1.6
                   *->kLpaPfrssdrvnllirsy<-*
                      ++  P+++ d+++ li+++
     R03G8.3   483    GF--PHSDKDFHKFLIKHR    499

Sulfatase: domain 1 of 1, from 501 to 514: score 2.9, E = 2.1
                   *->lldNTlvifTSDnG<-*
                      +ldN +v+f+ D+G
     R03G8.3   501    QLDNSFVFFMGDHG    514

DUF229: domain 2 of 3, from 444 to 668: score 167.5, E = 1.1e-46
                   *->rrplhevllDylrqFlpryrdspdipfFgFfWsnslsHddfnlasal
                      +r++h++llDyl qF+++y d++    F++ W + l Hd+ n+  +
     R03G8.3   444    CREDHHTLLDYLSQFINAYPDQN---KFRWIWASILGHDSENGFPHS 487

                   DedllkyLkkleenGlldntivifmSDHGlRfGklrrtsqGmlEERlPfm
                   D+d++k+L k+ e+  ldn++v+fm+DHGlRfG++r+t+ G l+ ++Pf+
     R03G8.3   488 DKDFHKFLIKHREQ--LDNSFVFFMGDHGLRFGNVRKTFVGTLDVSNPFL 535

                   sillPpwlRnyekyPqaveNLelNahrLtTpFDlHaTLkhilnlsslsdk
                    +++P+ lR   +   ++   + Na + +T+FD +aT+ +il+ +s s++
     R03G8.3   536 AVSIPKNLR---QTTGLLNVMRENAQKIQTHFDTRATMLDILKYQSASNF 582

                   ellrrtkaldclpsalprgiSLFlPiPdn.RtCstAgIpehwCtCe.syk
                    +l+ + ++ +      +g+S+++ +Pd  R+C   +Ip ++C+C+ ++
     R03G8.3   583 TDLDPLIIPGE------KGYSYIRTQPDIlRNCRNMPIPMQYCICQfNKT 626

                   eiptndtkekalvrriAekvvdriNellkelnteeElltplCapLeLqkV
                   +++t+ +     ++  +e+v  ++N++++e +     +t+ C+ ++ + V
     R03G8.3   627 QVSTKSE----TAKGVGEAVALAVNNEIEEGK-----FTDKCVKMKVDHV 667

                   e<-*

     R03G8.3   668 V    668

DUF229: domain 3 of 3, from 714 to 746: score 10.1, E = 0.038
                   *->vvdriNellkelntee.ElltplCapLeLqkVe<-*
                      +v+r N++  ++ ++ +E ++p+C++  ++k e
     R03G8.3   714    MVERSNKYGSTAYCIGsEHHRPYCYCKNQSKLE    746



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