Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/R05H5.4
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Query: R05H5.4 CE02291 tyrosine-protein kinase (FES\/FPS subfamily) status:Partially_confirmed TR:Q21764 protein_id:CAA88727.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
pkinase Protein kinase domain 225.9 5.7e-64 1
SH2 SH2 domain 10.0 0.033 1
HR1 Hr1 repeat 7.6 0.67 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
SH2 1/1 16 38 .. 1 27 [. 10.0 0.033
pkinase 1/1 120 369 .. 1 290 [. 225.9 5.7e-64
HR1 1/1 365 390 .. 62 87 .] 7.6 0.67
Alignments of top-scoring domains:
SH2: domain 1 of 1, from 16 to 38: score 10.0, E = 0.033
*->WyhGkIsRkeAErlLlnpggkdGtFLv<-*
++hG++ +A +lL n +G+F+v
R05H5.4 16 YFHGALMNIDADQLLVN----EGDFMV 38
pkinase: domain 1 of 1, from 120 to 369: score 225.9, E = 5.7e-64
*->yelleklGeGsfGkVykakhkdktgkiVAvKilkkekesikek.rfl
+ +k+G+G++G+Vy++k++ kt++ AvK+l++e +++ +
R05H5.4 120 VIFQKKIGAGAYGTVYRGKLV-KTDEVIAVKKLDPEGADEDGLaEMM 165
rEiqilkrLsHpNIvrligvfedtddhlylvmEymegGdLfdylrrnggp
E+++++ +HpNIv+++g+ +d ++ lv+Ey++gG d+lr++g +
R05H5.4 166 KEARVMQLYDHPNIVKFHGFIL-DDLPYLLVLEYCNGGAVEDRLRDKGEK 214
lsekeakkialQilrGleYLHsngivHRDLKpeNILldendgtvKiaDFG
+ + +k+++ ++G++YLH ++++HRD++++N+L+++ +vK aDFG
R05H5.4 215 IKVPTRVKYTYMAACGMDYLHKKNCIHRDIASRNCLIHKG--VVKMADFG 262
LArlle.sssklttfvGTpwYmmAPEvilegrgysskvDvWSlGviLyEl
++r + + l+ + +++ APEv + + Dv+++G++++E
R05H5.4 263 MCRAQSvYKVDLKKPC-NIRWL-APEV-WDNGETRFNTDVYAFGIMMWEF 309
ltggplfpgadlpaftggdevdqliifvlklPfsdelpktridpleelfr
+ ++Pf+ e+ +
R05H5.4 310 F----------------------------ETPFKS-------PYVEMKAA 324
iikrp...glrlplpsncSeelkdLlkkcLnkDPskRpGsatakeiln<-
+kr+++ g+rlp+p++ ++ + +++++c+++D++kRp ta+e+++
R05H5.4 325 QVKRKtraGYRLPPPPSMPSRMVEIMSECWQVDAEKRP---TAEELKE 369
*
R05H5.4 - -
HR1: domain 1 of 1, from 365 to 390: score 7.6, E = 0.67
*->elLkqsLerLeelhqdsdpegesdte<-*
e+Lk++Le++++++ +s +++ ++t+
R05H5.4 365 EELKEKLEEFKKKTENSITTSAPPTS 390