Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/R06A4.4a
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Query: R06A4.4a CE18111 locus:imb-2 Armadillo\/beta-catenin-like repeats (2 domains) status:Partially_confirmed TR:O62332 protein_id:CAB05586.
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
IBN_NT Importin-beta N-terminal domain 70.2 1.1e-17 1
Armadillo_seg Armadillo/beta-catenin-like repeat 15.2 0.016 5
HEAT HEAT repeat 9.3 0.43 3
DDT DDT domain 8.8 0.51 1
ANATO Anaphylotoxin-like domain 1.0 8.2 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
IBN_NT 1/1 31 100 .. 1 85 [] 70.2 1.1e-17
Armadillo_seg 1/5 129 156 .. 14 40 .] 1.2 1.5e+02
Armadillo_seg 2/5 200 239 .. 1 40 [] 1.8 1e+02
DDT 1/1 205 240 .. 25 63 .] 8.8 0.51
HEAT 1/3 362 380 .. 21 39 .] 1.9 70
HEAT 2/3 381 418 .. 1 39 [] 6.9 2.3
Armadillo_seg 3/5 430 457 .. 14 40 .] 3.2 42
Armadillo_seg 4/5 473 495 .. 16 34 .. 0.1 3.3e+02
ANATO 1/1 600 605 .. 32 37 .] 1.0 8.2
HEAT 3/3 670 690 .. 19 39 .] 0.5 1.9e+02
Armadillo_seg 5/5 705 729 .. 17 40 .] 10.8 0.29
Alignments of top-scoring domains:
IBN_NT: domain 1 of 1, from 31 to 100: score 70.2, E = 1.1e-17
*->AEkqLeqlekqdlPgfllaLlqIlansddssdlevRqlAalyLKNlI
+ qL ql++++ f+ +L++Il+++++ +d +R lA+l+LKN+I
R06A4.4a 31 VQVQLVQLNEHQ--KFCCYLVYILSDMKEMIDATSRSLAGLLLKNNI 75
trhWssheeqggyeqrplslpeeekeqIknnllnllls<-*
+++W+ + p+++k ++++++l+++++
R06A4.4a 76 RAKWN-------------KYPQDVKFFVRTTCLKSIGD 100
Armadillo_seg: domain 1 of 5, from 129 to 156: score 1.2, E = 1.5e+02
*->lppLvqLLs.pdeevqeeAawALsNLaa<-*
l L L++pde +qe A++AL
R06A4.4a 129 LDTLATVLMqPDELMQEGALGALQKVFE 156
Armadillo_seg: domain 2 of 5, from 200 to 239: score 1.8, E = 1e+02
*->npenkqavveaGalppLvqLLs....pdeevqeeAawALsNLaa<-*
n+++++ +++ L +L +++++deevq++ ++ L+ L +
R06A4.4a 200 NNDPIDFAIDQ----FLTSLFArhndNDEEVQKQLCRSLTLLLD 239
DDT: domain 1 of 1, from 205 to 240: score 8.8, E = 0.51
*->PftlddfiaaLleglldqsdllgEvhllLlRallreedd<-*
+f +d+f+++L + +d+ Ev+ +L R+l+ +d+
R06A4.4a 205 DFAIDQFLTSLFA---RHNDNDEEVQKQLCRSLTLLLDT 240
HEAT: domain 1 of 3, from 362 to 380: score 1.9, E = 70
*->epeVRlaaaesLgklakvl<-*
++++R+ a sL +la+++
R06A4.4a 362 DWNIRRCSAASLDVLASIF 380
HEAT: domain 2 of 3, from 381 to 418: score 6.9, E = 2.3
*->gpeitkeeLlPllldLakDeepeVRlaaaesLgklakvl<-*
g++ ++ +L Pll+d + +++ V+++ + +Lg++a+ +
R06A4.4a 381 GKDLLD-KLFPLLKDTLMNDNWLVKESGILALGAIAEGC 418
Armadillo_seg: domain 3 of 5, from 430 to 457: score 3.2, E = 42
*->lppLvqLLs.pdeevqeeAawALsNLaa<-*
+p + ++ ++++ v+ +w+Ls ++
R06A4.4a 430 IPFMLAMMFdKKPLVRSITCWTLSRYSS 457
Armadillo_seg: domain 4 of 5, from 473 to 495: score 0.1, E = 3.3e+02
*->pLvqLLs....pdeevqeeAawA<-*
+L +LL+ + +++ +vqe+A+ A
R06A4.4a 473 VLANLLRcsldGNKKVQEAACSA 495
ANATO: domain 1 of 1, from 600 to 605: score 1.0, E = 8.2
*->aFlqCC<-*
+F +CC
R06A4.4a 600 VFTRCC 605
HEAT: domain 3 of 3, from 670 to 690: score 0.5, E = 1.9e+02
*->DeepeVRlaaaesLgklakvl<-*
D +p+VR ++ Lg+l k++
R06A4.4a 670 DVTPDVRQSCFALLGDLTKAC 690
[output cut off at A = 10 top alignments]