Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm4/seq/R09E10.3
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Query:  R09E10.3  CE23909   long-chain-fatty-acid-CoA ligase status:Partially_confirmed TR:Q21872 protein_id:CAA94298.2

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N
--------        -----------                             -----    ------- ---
AMP-binding     AMP-binding enzyme                      266.0    4.9e-76   2
gla             Vitamin K-dependent carboxylation/gam    11.5      0.052   1
Nairo_nucleocap Nucleocapsid N protein                    3.7       0.67   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
gla               1/1     287   311 ..    18    42 .]    11.5    0.052
AMP-binding       1/2     116   384 ..     1   218 [.   124.0  2.7e-33
Nairo_nucleocap   1/1     472   491 ..   425   444 .]     3.7     0.67
AMP-binding       2/2     418   580 ..   208   373 .]   142.0  1.1e-38

Alignments of top-scoring domains:
gla: domain 1 of 1, from 287 to 311: score 11.5, E = 0.052
                   *->CeleearEefedtegtkefyrkYyg<-*
                      C+    +Eefe+++g + +y +Y
    R09E10.3   287    CSATMSCEEFENEAGVQDAYLSYLP    311

AMP-binding: domain 1 of 2, from 116 to 384: score 124.0, E = 2.7e-33
                   *->TYrELderanrlAaaLr..alGvgpGdrVaillpnspelvvailAvl
                      +Y +  e ++   +a r+ +  +g ++ ++i++ n+pe++ + +A++
    R09E10.3   116    SYDQAFETSDHASQAIRklGIEIGEESKIGIYSNNRPEWILSEMAIH 162

                   kaGaayvPldpsypaerlayiledsgakllltddallarl..........
                       + vPl+ + + + + yi + ++++l+++d++ + +    +++  ++
    R09E10.3   163 NFSNVSVPLYDTITNDDMHYITNLCEISLMFVDAEIKTKQlirdksylss 212

                   .....................................s.e.p.ppvdpdd
                    +  +   + +++ ++ + + +    +  + ++ +++++ +p++p++p+
    R09E10.3   213 lkyivqfnecsddikemarendfrlwsfnefvemgkkQkHrPhVPPTPET 262

                   lAyiiYTSGTTGkPKGVmltHrnlvnlvaala.rf.l.pddaervlllap
                   lA+i +TSGTTG+PKGVmltH n+++ ++++ +  +    + + +l+++p
    R09E10.3   263 LATISFTSGTTGRPKGVMLTHLNMCSATMSCEeFEnEaGVQ-DAYLSYLP 311

                   plyhfdgsvwelfgpLlaGatlvlvpkftryrdp.alldliekykvTvlf
                     +++    ++l++  + G ++ + ++++    p++l+d++++  +  +
    R09E10.3   312 --LAHIYERLCLLSNFMIGSRIGF-SRGD----PkLLVDDVQALAPRSFA 354

                   lvPtllrlllaape...dlssLrlvlsgGe<-*
                   +vP++++ + +a  ++ + + L+ +++ ++
    R09E10.3   355 TVPRVIDKIHKAVMkqvQDKPLKKMILNAA    384

Nairo_nucleocap: domain 1 of 1, from 472 to 491: score 3.7, E = 0.67
                   *->vqNPCAstIvkLfeiqkiGy<-*
                      v+ P A+   kL+++++ Gy
    R09E10.3   472    VGPPMACAMIKLIDVPELGY    491

AMP-binding: domain 2 of 2, from 418 to 580: score 142.0, E = 1.1e-38
                   *->ssLrlvlsgGealppellrrlrerfgsggvrlvngYGpTEttvvata
                      +++r +++g+++ +++++r +r +fg   v++++gYG+TEt++ +t
    R09E10.3   418    PNIRQLILGAAKSDVSAMRFARGAFG---VEVLEGYGQTETSGPTTL 461

                   nppg.d.pgsiGrPlpgvevyvlDeeg.rpvppGevGELyirGwpgvarG
                   +++g+++ g++G+P++++ ++++D        +   GE++++G  +v+ G
    R09E10.3   462 QLVGdTrIGCVGPPMACAMIKLIDVPElGYSVDKNGGEVLVKG-HNVTSG 510

                   YlnrPelTaerFvadgwgRmYrTGDlarwdpDGyleilGRiDdqvKi.rG
                   Y+++Pe+Ta++F++dg+   ++TGD++r++++G l i++R ++++K + G
    R09E10.3   511 YYKNPEATASSFTEDGY---MKTGDIGRFTAEGSLQIIDRRKNVFKMpQG 557

                   erIepgEiEavLlehPgVaeAaV<-*
                     ++p   E+ + +   V+++ V
    R09E10.3   558 KFVAPDLTESLYTSSSFVQQIYV    580



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