Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/R13G10.2
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Query: R13G10.2 CE25088 monoamine oxidase status:Partially_confirmed SW:Q21988 protein_id:CAA84671.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Amino_oxidase Flavin containing amine oxidoreductase 293.3 2.9e-84 1
DAO FAD dependent oxidoreductase 23.0 2.6e-05 1
pyr_redox Pyridine nucleotide-disulphide oxidored 20.4 4.2e-05 1
FMO-like Flavin-binding monooxygenase-like 12.6 0.012 1
FAD_binding_3 FAD binding domain 11.2 0.019 1
TrkA-N TrkA-N domain 10.1 0.27 1
SWIRM SWIRM domain 7.9 0.88 1
Thi4 Thi4 family 3.8 2 1
NAD_Gly3P_dh NAD-dependent glycerol-3-phosphate dehy 2.3 9 1
GLF UDP-galactopyranose mutase 1.3 5.4 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
SWIRM 1/1 238 259 .. 41 62 .. 7.9 0.88
NAD_Gly3P_dh 1/1 310 319 .. 1 10 [. 2.3 9
FMO-like 1/1 310 327 .. 1 18 [. 12.6 0.012
FAD_binding_3 1/1 313 338 .. 1 26 [. 11.2 0.019
TrkA-N 1/1 312 338 .. 1 27 [. 10.1 0.27
DAO 1/1 311 343 .. 1 36 [. 23.0 2.6e-05
pyr_redox 1/1 312 347 .. 1 47 [. 20.4 4.2e-05
Thi4 1/1 313 347 .. 30 66 .. 3.8 2
GLF 1/1 531 561 .. 64 93 .. 1.3 5.4
Amino_oxidase 1/1 320 772 .. 1 426 [] 293.3 2.9e-84
Alignments of top-scoring domains:
SWIRM: domain 1 of 1, from 238 to 259: score 7.9, E = 0.88
*->YLeyRnsiislwrlnpgryltf<-*
YL++Rn+ii++w++ p +lt+
R13G10.2 238 YLQVRNTIIAMWLKHPFVELTV 259
NAD_Gly3P_dh: domain 1 of 1, from 310 to 319: score 2.3, E = 9
*->pkkvtVlGaG<-*
++k++++GaG
R13G10.2 310 RPKIAIIGAG 319
FMO-like: domain 1 of 1, from 310 to 327: score 12.6, E = 0.012
*->aKkVAVIGAGVSGLaSiK<-*
+k+A+IGAG+SG + ++
R13G10.2 310 RPKIAIIGAGISGISTAR 327
FAD_binding_3: domain 1 of 1, from 313 to 338: score 11.2, E = 0.019
*->VLIVGgGPaGLmlAllLaraGvrvvv<-*
+I+G+G +G ++A+ L + G+++v+
R13G10.2 313 IAIIGAGISGISTARHLKHLGIDAVL 338
TrkA-N: domain 1 of 1, from 312 to 338: score 10.1, E = 0.27
*->hfiviGlGrvGrsvakeLleeGhdVvv<-*
+++iG+G G+s a+ L++ G+d v+
R13G10.2 312 KIAIIGAGISGISTARHLKHLGIDAVL 338
DAO: domain 1 of 1, from 311 to 343: score 23.0, E = 2.6e-05
*->mdvvVIGgGViGlgtAldlalrGqgtlkvalvevrd<-*
++++IG+G++G +tA++l G + +l+e++d
R13G10.2 311 PKIAIIGAGISGISTARHLKHLG---IDAVLFEAKD 343
pyr_redox: domain 1 of 1, from 312 to 347: score 20.4, E = 4.2e-05
*->dvvIIGgGpAGlaAAiraaragflGrkrlkvalvEkepplkrgtlGG
+++IIG+G G ++A+++ lG ++ +l+E+ + GG
R13G10.2 312 KIAIIGAGISGISTARHLKH---LG---IDAVLFEAK-----DRFGG 347
<-*
R13G10.2 - -
Thi4: domain 1 of 1, from 313 to 347: score 3.8, E = 2
*->VvIVGAGpSGLtAAYyLAkkRPglKVaiiErslSpGG<-*
++I GAG SG ++A+ L g +++E++ +GG
R13G10.2 313 IAIIGAGISGISTARHLKHL--GIDAVLFEAKDRFGG 347
GLF: domain 1 of 1, from 531 to 561: score 1.3, E = 5.4
*->dVrLNCktdflev.rdeldgqllFanesiak<-*
d+rLNC++ +++ +rd + +++F n++ a+
R13G10.2 531 DIRLNCPVKCIDWgRDDRKVKIFFENAEQAA 561
Amino_oxidase: domain 1 of 1, from 320 to 772: score 293.3, E = 2.9e-84
*->laGLaAAreLlraGf.VtvlEArdRvGGRvrtvrlkggdadgfliel
++G+++Ar+L++ G++ +++EA dR+GGR+ +++ g+ +
R13G10.2 320 ISGISTARHLKHLGIdAVLFEAKDRFGGRMMDDQS-----LGVSVGK 361
Gamwflgaypnvlnlllelglelglelppft...................
Ga+++ g+++n+ +ll+e++++ +++++f++ +++++ ++++ ++
R13G10.2 362 GAQIIVGNINNPITLLCEQIGIKYRNSNFFCplidengrcftlerkeldd 411
..................................elleldlesfsdllla
+ + ++ + +++ ++++ ++ + + + + ++e+ + s+ll+a
R13G10.2 412 qvdlhynnvldairnkyqsdrnfpdvplevtnfrHFTEMFSKMSSGLLSA 461
ggflel.......ll.galeflele.sarlallslrllgledgggtfpgg
+++++l +++ ++ll+++l+ le++ ++++ +ls+++ ++ + +g+f+g
R13G10.2 462 ADLDSLytpefekLLdFHLGNLEFScGTHVSNLSAKDYDHNEKFGNFAGE 511
glllplGglpvllaaaagllggrvrlnapVrkisqegdgdsndsgaenvt
++++ +G + +++ +a gl+ +rln+pV+ i++++d+ ++v+
R13G10.2 512 HAVITDGAQRIIDFLATGLD---IRLNCPVKCIDWGRDD-------RKVK 551
vttvdGekltkgdesetieaDaVivtvPlgvlk......flPpLpaakqe
+ +++ e + +e+D V++t++l+vlk+++++ f+PpLp +kq
R13G10.2 552 IFFENAE-------QAAEEFDKVVITTSLSVLKsnhskmFVPPLPIEKQK 594
airrlgfgsvsKvflefetpfwpeng.dhlfgavkgdlfgflvtdge.ls
ai+ lg g + K+++ f+++fw++ + d+ +++++fg + + + ++s
R13G10.2 595 AIDDLGAGLIEKIAVKFDRRFWDTVDaDG----LRTEYFGKVSDCKTdRS 640
rgeyvldtsktdgsapewgrgvllsyvlgdgannreledlsdeelleavl
+ +++d+s +d+++ + vl+syv ++++ + l++ e++++++
R13G10.2 641 LFNIFYDFSGKDPNGE--DTFVLMSYVTAEHV--NLVNVLTESEVADKFC 686
edLrkllgsdfedvpdPvtagdyrdtvvtrWstdpfprgsysyppvgad.
Lrk+++ ++v +P + +++++W++d+f + sy+++p g d+
R13G10.2 687 ATLRKMFP---SAVINPLG------HMMSHWGADRFVGMSYTFVPFGSDg 727
..drpalrePvgnenpkdgdpglyfAGehtsgvypgtveGAveSGlraAr
+ ++ +l+ ++ + lyfAGeht p+t+ GA+ SGlr+A
R13G10.2 728 daTYNQLKKSID--------EKLYFAGEHTIAAEPQTMAGAYISGLREAG 769
ril<-*
+i
R13G10.2 770 QIV 772
[output cut off at A = 10 top alignments]