Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/T05A12.4
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: T05A12.4 CE26384 helicase status:Partially_confirmed TR:Q9GYK7 protein_id:AAF98590.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
SNF2_N SNF2 family N-terminal domain 85.2 1.6e-22 1
helicase_C Helicase conserved C-terminal domain 36.2 8.8e-09 1
zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 16.3 6.9e-05 1
DUF683 Protein of unknown function (DUF683) 11.3 0.12 1
PHD PHD-finger 4.9 2.2 1
HgmA homogentisate 1,2-dioxygenase 1.8 8.8 1
HSP70 Hsp70 protein 1.1 9.3 1
DUF163 Uncharacterized ACR, COG1576 0.0 9.7 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
HgmA 1/1 89 103 .. 460 474 .] 1.8 8.8
DUF163 1/1 238 244 .. 157 163 .] 0.0 9.7
PHD 1/1 474 486 .. 39 51 .] 4.9 2.2
SNF2_N 1/1 316 650 .. 1 223 [. 85.2 1.6e-22
DUF683 1/1 1073 1101 .. 39 67 .] 11.3 0.12
HSP70 1/1 1087 1108 .. 599 620 .] 1.1 9.3
zf-C3HC4 1/1 1334 1380 .. 1 50 [] 16.3 6.9e-05
helicase_C 1/1 1478 1525 .. 25 72 .] 36.2 8.8e-09
Alignments of top-scoring domains:
HgmA: domain 1 of 1, from 89 to 103: score 1.8, E = 8.8
*->qddYdkcWqgLkshf<-*
+++Y++ W +L++++
T05A12.4 89 DEEYIETWKDLPKNR 103
DUF163: domain 1 of 1, from 238 to 244: score 0.0, E = 9.7
*->irghPYH<-*
+ +h+YH
T05A12.4 238 TMKHKYH 244
PHD: domain 1 of 1, from 474 to 486: score 4.9, E = 2.2
*->pegkWlCpeCtpk<-*
+++k++C +Ct++
T05A12.4 474 KNEKFQCSKCTSE 486
SNF2_N: domain 1 of 1, from 316 to 650: score 85.2, E = 1.6e-22
*->YQleGvnWLislyknlvk.......................kendsc
YQ++ v+W+ ++ n +++++ + ++++ + +++++ e+
T05A12.4 316 YQKDTVRWMLYRELN--HepdgniewmiksekymtieerkdIEKRFT 360
glggILADEMGLGKTlQtIsllayllelkpkae.................
ggILADEMGLGKT+Q+ sl+a++ + ++ + +++++ ++ +++++++
T05A12.4 361 LKGGILADEMGLGKTIQALSLIATNRKHSKVEIydesgevetvnrdesks 410
..................................................
++++ ++ + +++ + ++ ++++ + + + ++ ++++ ++ ++
T05A12.4 411 tnssiaqqiklaessyaemkgarqnqadirynlnsfcdgetilcsncsqm 460
.............................k.rigpfLvVcPlStldnWln
+ + + + ++ ++++ + ++ ++++++ + g +L++ P+S++ +W
T05A12.4 461 csakicgwdfdkfknekfqcskctsesenRrAVGTTLIILPESLIFQWFT 510
EfekWapddlnivvyygdgnsrdqirkdellrnflkdggrlkydvlitsY
E+ k+++d++++ +y+g + l++ +d ydv++t+Y
T05A12.4 511 EISKHCSDNIKVMFYFGIRKHG-------YLQPCEMDS----YDVILTTY 549
eiirkNkLl...................kdkdeLkklginwdylilDEgH
+++r+ ++ +++++++++ ++++++ ++L++ +++ ++i+DE
T05A12.4 550 DTLRN--EMsfseekgpprnlrnesktlNLTSSLMH--VEFWRIIVDES- 594
HrlKNe..dSklrkskalnklkhtrnRLlLTGTPlQNnLkElwsLlnFlm
+ +++ S+l ++ l+kl + n ++ TGTPl +++ + L+nFl+
T05A12.4 595 -QVLPHgvSSQL--TRMLMKLH-AENWWCVTGTPLVKSIAGIYPLFNFLN 640
PgiFgsleeyindgksF<-*
+Fgs+ + F
T05A12.4 641 LFPFGSP-------QFF 650
DUF683: domain 1 of 1, from 1073 to 1101: score 11.3, E = 0.12
*->eildvArkTydafaeLdeakaeLaalEaa<-*
+++dv kT d f+ +de+++eL+ +++
T05A12.4 1073 SLPDVMSKTLDHFKKIDEKRKELDQKANK 1101
HSP70: domain 1 of 1, from 1087 to 1108: score 1.1, E = 9.3
*->eikakteeLqkvvqkigekmyq<-*
+i +k++eL++ +k++e +++
T05A12.4 1087 KIDEKRKELDQKANKLVEFIMK 1108
zf-C3HC4: domain 1 of 1, from 1334 to 1380: score 16.3, E = 6.9e-05
*->CrICleelkepsndfplilpCgHsGslkyfCrsClerWls...gntt
C+IC+ + ++ CgH+ C+ C e++ +++ +
T05A12.4 1334 CPICCAS-IDCF----MVFTCGHR-----ICQNCFEKMRAlqrRAGS 1370
....vkCplC<-*
++ v+Cp C
T05A12.4 1371 aedvVACPTC 1380
helicase_C: domain 1 of 1, from 1478 to 1525: score 36.2, E = 8.8e-09
*->ngkskvLvaTdvaarGiDipdvnlVInydlpwnpesyiQRiGRaGRa
+++ ++L++ ++ a G++ +++n++I++d+p +++ Q+iGR+ R+
T05A12.4 1478 EDTKVLLCSLSLCANGLNMTGANHIIFLDPPHLQSVLNQAIGRINRF 1524
G<-*
G
T05A12.4 1525 G 1525