Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm4/seq/T22B11.5
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Query:  T22B11.5  CE28486   2-oxoglutarate dehydrogenase status:Partially_confirmed TR:O61199 protein_id:AAB94185.2

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
E1_dehydrog  Dehydrogenase E1 component                 297.1    2.1e-85   1
transket_pyr Transketolase, pyridine binding domain     244.0    2.1e-69   1
Mg_chelatase Magnesium chelatase, subunit ChlI            5.1        1.5   1
CbiM         CbiM                                         3.4        8.7   1
PLRV_ORF5    Potato leaf roll virus readthrough prote     2.5        3.7   1
NiFeSe_Hases Nickel-dependent hydrogenase                 1.2        6.9   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
CbiM           1/1     354   376 ..     1    27 [.     3.4      8.7
PLRV_ORF5      1/1     527   549 ..   540   564 .]     2.5      3.7
E1_dehydrog    1/1     261   586 ..     1   327 []   297.1  2.1e-85
NiFeSe_Hases   1/1     633   642 ..     1    10 [.     1.2      6.9
transket_pyr   1/1     650   868 ..     1   188 []   244.0  2.1e-69
Mg_chelatase   1/1     865   892 ..   308   343 .]     5.1      1.5

Alignments of top-scoring domains:
CbiM: domain 1 of 1, from 354 to 376: score 3.4, E = 8.7
                   *->aivyglrrlrriveekPeqipLlalla<-*
                       +++++ rl+r++++     +++a++a
    T22B11.5   354    HLGVCIERLNRQSQKN----VKIAVVA    376

PLRV_ORF5: domain 1 of 1, from 527 to 549: score 2.5, E = 3.7
                   *->QRleYeRIkrslGkTaAaeYleell<-*
                      Q l Y+RIk +  kTa  +Y e+ l
    T22B11.5   527    QPLMYQRIKQT--KTALEKYQEKIL    549

E1_dehydrog: domain 1 of 1, from 261 to 586: score 297.1, E = 2.1e-85
                   *->yrmmllrRmedarmalykrqgirGFyhlyaGqEAlqvGiaaAldkgv
                      +r+ +++ +e++++ ++ +++++G++++++ ++A +  i+ +++ gv
    T22B11.5   261    KRLIRSTKFEEFLAKKWPSEKRFGLEGCEVLIPAMKQVIDSSSTLGV 307

                   DyviptmPYRdhgvllarGvsk.leevlaelyGreaGcskGkGGSmhmpg
                   D+ + +mP+R++ ++la++ + +l  +l+++   e  +++G+G++++++g
    T22B11.5   308 DSFVIGMPHRGRLNVLANVCRQpLATILSQFSTLE-PADEGSGDVKYHLG 356

                   yqkpknnrfyggngivgaqaqvpipaAvGiAlAakekreQfyvgdyrgkk
                     +++ nr    n  ++ +a++++ +Av++++++k ++e fy gd++ +
    T22B11.5   357 VCIERLNRQSQKNVKIAVVANPSHLEAVDPVVMGKVRAEAFYAGDEKCDR 406

                   evaitlfGDGAFtnqGqffEalNfAalwklPvgGaIFvceNNqyAisTpa
                    +ai+l+GD+AF++qG + E++N+ +l++++++GaI++++NNq++++T++
    T22B11.5   407 TMAILLHGDAAFAGQGVVLETFNLDDLPSYTTHGAIHIVVNNQIGFTTDP 456

                   erssasteyadrArGygIPgirVDGmDplAVyqAvKeAaerartGkGPtL
                   + s++s++ +d++r++g P+++V+ +Dp+AV+ ++ +Aa++++t+k++++
    T22B11.5   457 RSSRSSPYCTDVGRVVGCPIFHVNVDDPEAVMHVCNVAADWRKTFKKDVI 506

                   IElvTYRygGHsmsDdpstYRtreeveevrkkkDPikrlkkhLvskGlas
                   ++lv+YR++GH++ D+p++++ + +++ ++++k+ +++++++++++G+a+
    T22B11.5   507 VDLVCYRRHGHNELDEPMFTQ-PLMYQRIKQTKTALEKYQEKILNEGVAN 555

                   eeElkeiekevrkeieeAvkkAesapepnpe<-*
                   e  +ke+  ++  + e+A++ A   +++ +
    T22B11.5   556 EQYVKEELTKYGSILEDAYENAQKVTYVRNR    586

NiFeSe_Hases: domain 1 of 1, from 633 to 642: score 1.2, E = 6.9
                   *->RGLEkILkGR<-*
                      RGLE  LkGR
    T22B11.5   633    RGLERTLKGR    642

transket_pyr: domain 1 of 1, from 650 to 868: score 244.0, E = 2.1e-69
                   *->kiatrkAfgeALaelaerdprVvglgaDvgaygGtftvtkglldpqg
                      +++++ ++++A+++l++++ +V+++g+Dv   +Gtf++++++l++q+
    T22B11.5   650    SLDWACGEALAFGSLLKEGIHVRLSGQDVQ--RGTFSHRHHVLHDQK 694

                   .................egRvidtgiaEqamvGfanGlAlaGpnllppve
                    +++  ++ ++ +++++e+ v+++ ++E+a++Gf+ G+++  pn l+++e
    T22B11.5   695 vdqkiynplndlsegqgEYTVCNSSLSEYAVLGFELGYSMVDPNSLVIWE 744

                   aqFgdFlnpAfdQiradaairryralgklpvpfvvtrapiGvGedGptHh
                   aqFgdF+n  ++Q+++d++i+++ +++ ++++ +v+++p+G++++Gp+H+
    T22B11.5   745 AQFGDFSN--TAQCIIDQFISSGQSKWIRQSG-LVMLLPHGYEGMGPEHS 791

                   sqedeaflraiPg....................e.nNlkVvrPsdpaeak
                   s+++e+fl+++  +++ + ++   +++ + ++ ++ N++V+++++pa+++
    T22B11.5   792 SARPERFLQMCNEddeidlekiafegtfeaqqlHdTNWIVANCTTPANIY 841

                   glLraAirsdrddddPvvfreprqllrhk<-*
                   +lLr+++   +++++P v++ p++llrh+
    T22B11.5   842 HLLRRQVT--MPFRKPAVVFSPKSLLRHP    868

Mg_chelatase: domain 1 of 1, from 865 to 892: score 5.1, E = 1.5
                   *->LrhRsvLrddplepsrtpppvlskikvqarfeevfa<-*
                      Lrh+  + + p+e+ +      s++++q++  e  a
    T22B11.5   865    LRHP--MARSPVEDFQ------SGSNFQRVIPETGA    892



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