Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/T24A11.3
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Query: T24A11.3 CE30398 locus:toh-1 zinc metalloprotease status:Partially_confirmed TR:Q22710 protein_id:CAA88882.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Astacin Astacin (Peptidase family M12A) 286.7 2.9e-88 1
CUB CUB domain 17.7 0.00057 1
Zn_peptidase Putative neutral zinc metallopeptidase 5.9 0.66 1
DSL Delta serrate ligand 5.6 2.4 1
Peptidase_M7 Streptomyces extracellular neutral prote 3.6 6.5 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Zn_peptidase 1/1 125 138 .. 201 214 .. 5.9 0.66
Peptidase_M7 1/1 129 147 .. 81 99 .. 3.6 6.5
Astacin 1/1 50 243 .. 1 200 [] 286.7 2.9e-88
DSL 1/1 268 278 .. 57 67 .] 5.6 2.4
CUB 1/1 286 327 .. 1 50 [. 17.7 0.00057
Alignments of top-scoring domains:
Zn_peptidase: domain 1 of 1, from 125 to 138: score 5.9, E = 0.66
*->AqaYVIAHEVGHHV<-*
A++YV+AHE GH++
T24A11.3 125 AEEYVVAHETGHAL 138
Peptidase_M7: domain 1 of 1, from 129 to 147: score 3.6, E = 6.5
*->vtaHEtGHvLGLPDhYsGP<-*
v aHEtGH LG + + P
T24A11.3 129 VVAHETGHALGFWHTHQRP 147
Astacin: domain 1 of 1, from 50 to 243: score 286.7, E = 2.9e-88
*->rrWpngsGiVvIPYvisssysgrersliraAmrhwenkTCirFvprt
++ p++ + s +s++ +slir+++r+we++TC+rF++++
T24A11.3 50 NLLPSN--------TKSLLFSDNFQSLIRRGIRMWEDSTCLRFKENQ 88
sagendylrff.sgdGCwSyVGrrggGaeQevSlganGCdyfGtivHElg
+ ++ ++ ++ ++gd C+ ++++r +G +Q++ +g ++C++ ++++HE+g
T24A11.3 89 Q-SRDAIRYVLeKGDSCFTEYIGR-NGGHQDIIIG-SECAEEYVVAHETG 135
HALGFwHEQsRpDRDdyVsInwqNIdpgqeynFdKyd.......pdqvds
HALGFwH+++RpDRD+++sInw+N++++++ F+ + + + +qv+
T24A11.3 136 HALGFWHTHQRPDRDRHISINWKNVMEEATASFMPFRsmlqafgIRQVSP 185
lGvPYDYgSiMHYgpyaFSkngskpTIvpkdnkvyqatiGQReglSflDi
+ vPYDYgS MHY++ a+++ s+ TIvpk+ k y +t+G + ++flD+
T24A11.3 186 RRVPYDYGSLMHYHAVAHAVKVSDFTIVPKELK-YVTTMGTEK-MAFLDA 233
kkiNklYnCpe<-*
k iN +Y Cp+
T24A11.3 234 KVINDIY-CPN 243
DSL: domain 1 of 1, from 268 to 278: score 5.6, E = 2.4
*->lCleGWkGeyC<-*
+C+eG+ G++C
T24A11.3 268 RCPEGLGGPDC 278
CUB: domain 1 of 1, from 286 to 327: score 17.7, E = 0.00057
*->CGgtldltessGsisSPnYPnrsdYppnkeCvWrIrappgyrvVeLt
CGg++ + ++sS + ++++C+WrI++p+g+r V ++
T24A11.3 286 CGGEIHASDQWQTLSS-------PSGRDVHCYWRISVPEGSR-VRFR 324
Fqd<-*
d
T24A11.3 325 LSD 327