Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm4/seq/T24A11.3
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Query:  T24A11.3  CE30398  locus:toh-1 zinc metalloprotease status:Partially_confirmed TR:Q22710 protein_id:CAA88882.2

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
Astacin      Astacin (Peptidase family M12A)            286.7    2.9e-88   1
CUB          CUB domain                                  17.7    0.00057   1
Zn_peptidase Putative neutral zinc metallopeptidase       5.9       0.66   1
DSL          Delta serrate ligand                         5.6        2.4   1
Peptidase_M7 Streptomyces extracellular neutral prote     3.6        6.5   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
Zn_peptidase   1/1     125   138 ..   201   214 ..     5.9     0.66
Peptidase_M7   1/1     129   147 ..    81    99 ..     3.6      6.5
Astacin        1/1      50   243 ..     1   200 []   286.7  2.9e-88
DSL            1/1     268   278 ..    57    67 .]     5.6      2.4
CUB            1/1     286   327 ..     1    50 [.    17.7  0.00057

Alignments of top-scoring domains:
Zn_peptidase: domain 1 of 1, from 125 to 138: score 5.9, E = 0.66
                   *->AqaYVIAHEVGHHV<-*
                      A++YV+AHE GH++
    T24A11.3   125    AEEYVVAHETGHAL    138

Peptidase_M7: domain 1 of 1, from 129 to 147: score 3.6, E = 6.5
                   *->vtaHEtGHvLGLPDhYsGP<-*
                      v aHEtGH LG   + + P
    T24A11.3   129    VVAHETGHALGFWHTHQRP    147

Astacin: domain 1 of 1, from 50 to 243: score 286.7, E = 2.9e-88
                   *->rrWpngsGiVvIPYvisssysgrersliraAmrhwenkTCirFvprt
                      ++ p++        + s  +s++ +slir+++r+we++TC+rF++++
    T24A11.3    50    NLLPSN--------TKSLLFSDNFQSLIRRGIRMWEDSTCLRFKENQ 88

                   sagendylrff.sgdGCwSyVGrrggGaeQevSlganGCdyfGtivHElg
                   + ++ ++ ++ ++gd C+ ++++r +G +Q++ +g ++C++ ++++HE+g
    T24A11.3    89 Q-SRDAIRYVLeKGDSCFTEYIGR-NGGHQDIIIG-SECAEEYVVAHETG 135

                   HALGFwHEQsRpDRDdyVsInwqNIdpgqeynFdKyd.......pdqvds
                   HALGFwH+++RpDRD+++sInw+N++++++  F+   +  +  + +qv+
    T24A11.3   136 HALGFWHTHQRPDRDRHISINWKNVMEEATASFMPFRsmlqafgIRQVSP 185

                   lGvPYDYgSiMHYgpyaFSkngskpTIvpkdnkvyqatiGQReglSflDi
                   + vPYDYgS MHY++ a+++  s+ TIvpk+ k y +t+G  + ++flD+
    T24A11.3   186 RRVPYDYGSLMHYHAVAHAVKVSDFTIVPKELK-YVTTMGTEK-MAFLDA 233

                   kkiNklYnCpe<-*
                   k iN +Y Cp+
    T24A11.3   234 KVINDIY-CPN    243

DSL: domain 1 of 1, from 268 to 278: score 5.6, E = 2.4
                   *->lCleGWkGeyC<-*
                      +C+eG+ G++C
    T24A11.3   268    RCPEGLGGPDC    278

CUB: domain 1 of 1, from 286 to 327: score 17.7, E = 0.00057
                   *->CGgtldltessGsisSPnYPnrsdYppnkeCvWrIrappgyrvVeLt
                      CGg++   +   ++sS       +  ++++C+WrI++p+g+r V ++
    T24A11.3   286    CGGEIHASDQWQTLSS-------PSGRDVHCYWRISVPEGSR-VRFR 324

                   Fqd<-*
                     d
    T24A11.3   325 LSD    327



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