Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm4/seq/T24F1.6
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Query:  T24F1.6  CE02366   calcium channel alpha-2 subunit status:Partially_confirmed TR:Q17517 protein_id:CAA90091.1

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N
--------        -----------                             -----    ------- ---
Cache           Cache domain                            118.8    6.9e-32   2
vwa             von Willebrand factor type A domain      11.9      0.008   1
Filamin         Filamin/ABP280 repeat                     3.8        7.6   1
Omt_N           O-methyltransferase N-terminus            3.8        8.1   1
Rotamase        PPIC-type PPIASE domain                   3.6        8.2   1
DUF324          Protein of unknown function (DUF324)      3.2        3.2   1
Adenylsucc_synt Adenylosuccinate synthetase               1.7          8   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
DUF324            1/1     101   147 ..   285   333 .]     3.2      3.2
vwa               1/1     315   354 ..     1    44 [.    11.9    0.008
Cache             1/2     525   609 ..     1    93 []   115.9  4.5e-31
Rotamase          1/1     685   693 ..     1     9 [.     3.6      8.2
Filamin           1/1     692   699 ..    93   100 .]     3.8      7.6
Adenylsucc_synt   1/1     873   882 ..     1    10 [.     1.7        8
Omt_N             1/1     885   900 ..    90   106 ..     3.8      8.1
Cache             2/2     911   934 ..    70    93 .]     2.9       22

Alignments of top-scoring domains:
DUF324: domain 1 of 1, from 101 to 147: score 3.2, E = 3.2
                   *->tifEilvkvnrefykevlefenkkerfkkveedfeklvydkleedkY
                      ti+E+ +++ + +  + ++fe    rf +v+e fekl  d+  + k+
     T24F1.6   101    TIEEAPASIAQFSANILRDFET-QSRFSLVQEEFEKLKPDIKSK-KE 145

                   le<-*

     T24F1.6   146 DA    147

vwa: domain 1 of 1, from 315 to 354: score 11.9, E = 0.008
                   *->DivFllDgSgSigeenrFekvkdfvkklveknldigpdgtrvgl<-*
                      DivFllD SgS+ +     ++k ++  +++  l  +p++  +g+
     T24F1.6   315    DIVFLLDYSGSVKGPT-MHLIKITMMYILS-TL--SPNDYFFGV    354

Cache: domain 1 of 2, from 525 to 609: score 115.9, E = 4.5e-31
                   *->wTePYvdaastgdlViTvsvPvydrtnetenktnkdngdllGVvgiD
                      wT+ Y++++ ++++++T+s+P+++      +++++++++l GVv+iD
     T24F1.6   525    WTQLYMETQ-GTGPIVTLSLPILT-----SEQRIWRDQKLAGVVAID 565

                   vpledLlkltksiklGktGYaFivdnnGkvlaHPnlrpvtkllkdw<-*
                   +++++++k+++    ++++Y +ivdnnG++++HP+l++++++++++
     T24F1.6   566 ISIKEFTKHLPTS--SEQMYGYIVDNNGMLIYHPQLQIPKTEVHCV    609

Rotamase: domain 1 of 1, from 685 to 693: score 3.6, E = 8.2
                   *->pkevrarHI<-*
                      +ke++++HI
     T24F1.6   685    SKEYHCSHI    693

Filamin: domain 1 of 1, from 692 to 699: score 3.8, E = 7.6
                   *->hiPgSPfk<-*
                      hi++SPf+
     T24F1.6   692    HIKDSPFT    699

Adenylsucc_synt: domain 1 of 1, from 873 to 882: score 1.7, E = 8
                   *->rnvVVlGsQW<-*
                      + ++V+G+QW
     T24F1.6   873    NRLAVVGTQW    882

Omt_N: domain 1 of 1, from 885 to 900: score 3.8, E = 8.1
                   *->rffDdyflaAlraaGir<-*
                      +ffD+yf++++ +++++
     T24F1.6   885    NFFDQYFDNFT-RQNPD    900

Cache: domain 2 of 2, from 911 to 934: score 2.9, E = 22
                   *->ivdnnGkvlaHPnlrpvtkllkdw<-*
                      i+++nG v+a   +r++ +l k++
     T24F1.6   911    IITRNGHVIASSAHRAPAHLAKFD    934



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