Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm4/seq/T25F10.6
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Query:  T25F10.6  CE07537   calponin-like protein status:Confirmed TR:Q23050 protein_id:AAB04989.1

Scores for sequence family classification (score includes all domains):
Model     Description                                   Score    E-value  N
--------  -----------                                   -----    ------- ---
calponin  Calponin family repeat                        160.0    4.8e-48   7
Filaggrin Filaggrin                                       3.3        4.3   1

Parsed for domains:
Model     Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------  ------- ----- -----    ----- -----      -----  -------
calponin    1/7     103   128 ..     1    26 []    34.0  5.7e-09
calponin    2/7     154   177 ..     1    26 []    22.9  1.6e-05
calponin    3/7     201   226 ..     1    26 []    30.3  7.6e-08
Filaggrin   1/1     233   240 ..    48    55 .]     3.3      4.3
calponin    4/7     241   266 ..     1    26 []    44.9  2.3e-12
calponin    5/7     290   310 ..     6    26 .]    10.8    0.088
calponin    6/7     325   350 ..     1    26 []    24.1  6.6e-06
calponin    7/7     383   398 ..    11    26 .]     9.4     0.24

Alignments of top-scoring domains:
calponin: domain 1 of 7, from 103 to 128: score 34.0, E = 5.7e-09
                   *->iGLqmGtnKgAsqaGmtaYGtprrli<-*
                      i +q G+nK+Asq+Gmt++G pr +i
    T25F10.6   103    IPIQAGSNKYASQKGMTGFGVPRDVI    128

calponin: domain 2 of 7, from 154 to 177: score 22.9, E = 1.6e-05
                   *->iGLqmGtnKgAsqaGmtaYGtprrli<-*
                        Lq GtnK+Asq+G +++G  r +
    T25F10.6   154    --LQSGTNKFASQKGQSGFGAVRDVN    177

calponin: domain 3 of 7, from 201 to 226: score 30.3, E = 7.6e-08
                   *->iGLqmGtnKgAsqaGmtaYGtprrli<-*
                      + Lq GtnK AsqaGmt+ G+pr +
    T25F10.6   201    VPLQSGTNKLASQAGMTGIGMPRIVD    226

Filaggrin: domain 1 of 1, from 233 to 240: score 3.3, E = 4.3
                   *->QdsDSEGH<-*
                      Qd+DS+G
    T25F10.6   233    QDRDSQGF    240

calponin: domain 4 of 7, from 241 to 266: score 44.9, E = 2.3e-12
                   *->iGLqmGtnKgAsqaGmtaYGtprrli<-*
                      i LqmGtnK+A qaGmt++G+pr+ i
    T25F10.6   241    IHLQMGTNKFANQAGMTGFGMPRHNI    266

calponin: domain 5 of 7, from 290 to 310: score 10.8, E = 0.088
                   *->GtnKgAsqaGmtaYGtprrli<-*
                      G   gAsqaGmt++G  r
    T25F10.6   290    GWKEGASQAGMTGFGAFRNNT    310

calponin: domain 6 of 7, from 325 to 350: score 24.1, E = 6.6e-06
                   *->iGLqmGtnKgAsqaGmtaYGtprrli<-*
                      i  qmG n   sqaG t++G+pr+++
    T25F10.6   325    IPYQMGVNFLESQAGKTGFGQPRQVY    350

calponin: domain 7 of 7, from 383 to 398: score 9.4, E = 0.24
                   *->AsqaGmtaYGtprrli<-*
                      A q Gmta+Gtpr +
    T25F10.6   383    ANQTGMTAFGTPRDVR    398



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