Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/T28D9.7
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Query: T28D9.7 CE28095 degenerin status:Partially_confirmed SW:Q10025 protein_id:AAA68309.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
ASC Amiloride-sensitive sodium channel 489.7 2.3e-143 1
GED Dynamin GTPase effector domain 5.8 2.3 1
PI3K_C2 C2 domain 5.5 2 1
SNase Staphylococcal nuclease homologue 4.1 7.6 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
PI3K_C2 1/1 453 504 .. 144 205 .] 5.5 2
GED 1/1 567 606 .. 60 97 .] 5.8 2.3
ASC 1/1 26 685 .. 19 622 .] 489.7 2.3e-143
SNase 1/1 763 771 .. 150 158 .] 4.1 7.6
Alignments of top-scoring domains:
PI3K_C2: domain 1 of 1, from 453 to 504: score 5.5, E = 2
*->sltWpskepdesvptsTPGKvplesrdelnrLekllkkyerGdvqpn
+l W + pd +++t ++ ++++r+++l+++ye ++ q+
T28D9.7 453 KL-WHVFMPDSYIRT------MTGDFSRMDRIIELMNQYELNKLQR- 491
pvvdwlDfltlreie<-*
w ++++r ++
T28D9.7 492 --RAWAEKMQSRQMK 504
GED: domain 1 of 1, from 567 to 606: score 5.8, E = 2.3
*->eelldeLLeEdpeias..kRkelkkrLelLkkArqiisev<-*
++++++L E +e as+++Rke k+L+ kk+++++ +
T28D9.7 567 RQKFEKLIVEMHECASgkMRKEAGKMLSSFKKSYRELQAA 606
ASC: domain 1 of 1, from 26 to 685: score 489.7, E = 2.3e-143
*->nrlrRafWlllvlvslglllwQigiliskYlskptvsvnielkfPve
+++++ +W+++++++++l+l+Q+++ i+ Y s+p v +nie ++P +
T28D9.7 26 YSRYKGLWCMIIIAFVILVLVQCYSQIKLYISEP-VATNIEAEYP-S 70
klpFPaVTiCNlNPykyse........vrsn.ivlelndtldaftllely
k+ FP+V iCN+N++++ + ++++ ++rs++i+ +l+ t++ +++++++
T28D9.7 71 KISFPTVAICNNNQFRLTYltggrimnRRSKsISGSLLSTGHDVESVFDT 120
sgs.ksemdalefnssrkrrskraqq.vrn.gks.lrg.rfplvfadcrl
++++++mda++f++s++++++r++ ++++++++++++++f++v+++++l
T28D9.7 121 VLRkSWDMDAVKFLRSAAHWKSRMILgCTWpNGTsCKLsDFKAVWTTTGL 170
dsqecv.deresrrtes..........lieipesvcicfgdrwkvgfwlC
++++++++++++++t+s+++++ + ++e++e+v++c++++++++++++
T28D9.7 171 CWAINTdPHNPYEVTGSgeghglrlllNVESYERVDACTKHFRTKTLPGL 220
s.nstWekeCsCndhfCpcicsdlecvkttriweplykqsaepep.e.me
+ ++ ++++p+++m+
T28D9.7 221 KiLIYN----------------------------------QTDIPdSsMN 236
tcedqgfssgtdevaewykakenlifaqaalseqfrislsysleeliltC
+ ++ +s++++++++++ k+++++++++++eq ++s ++ +e i tC
T28D9.7 237 GVNVPSGYSMDIPFKMQHRSKLTGVHCIEENDEQIEASTDFNNPENIRTC 286
sF........ngesCdicrdFtt.fidpsyGnC...YtFNsnrstsiyrd
+ ++ ++ +n+++C+ +r++t++ +d ++ +C+ + +F+++++++++++
T28D9.7 287 TLrrymteveNSCHCTLRRAYTSnSTDVKMKACnvdQYFGCAQKAMQRIR 336
e.............genlltssrpGp.leyGLrlvLdvnqdeylPtteat
e+++ ++ ++ ++++++ ++ + +++ + +l+ ++d+++++++++
T28D9.7 337 EegtastclppcksIDYTAWQDMNRLpQNLMPALIEEQEEDDEDDVEQEE 386
pdalfetsfeaGvrvfiHeqdevPfpdsfGysappGfessigvklkqltr
+d+++++s++ G f +e+++ P+++++ ++ ++ f ++ tr
T28D9.7 387 LDENVSFSTVSGGETFSCEDKSRPITSEEKKANQMFFLLDETAFNRNATR 436
Lp.v.elkapyGnCtedgedvpvenlYi........yiytnksYsieaCl
+++v++lk+ yG+ +e+ ++v+++++Yi++ +++ +++++ + + ++ l
T28D9.7 437 YMsVgDLKSRYGDKMEKLWHVFMPDSYIrtmtgdfsRMDRIIELMNQYEL 486
rsCfqryivekCGCa.......dpryPlyesplngakyCtpekhidcgcc
+ r + ek++ ++ ++ +d +y +y++pl + ++t +k+id+++
T28D9.7 487 NKLQRRAWAEKMQSRqmkhffeDDFYESYYQPLIKDLDTTLVKQIDEVEA 536
ylklldtflqeklgak............sndfsvecqckCkqpCneteYt
++ + ++lq+++++k++ ++++++n++++e + +++C + +++
T28D9.7 537 DWPKVEYYLQRGSAGKtgaimffgdgnkDNRQKFEKLIVEMHECASGKMR 586
vtySyakwPSaased.........wlgpvlskfesekeendlyrnNiaml
++++ + + +++s+++ + ++ ++++ ++ e+ + n+++++N+am+
T28D9.7 587 KEAGKMLSSFKKSYRelqaaygklFKEELPDYLENFQFGNKFVGDNFAMV 636
nIffeeLnYesikEspaygvvnLLSdiGGqlGLflGaSVlsvlElielf<
nIf++++n e+++++++yg+++L +diGG+lGLflGaS+l+++E+++l+
T28D9.7 637 NIFLHRMNLEVWSQDRTYGFWSLACDIGGALGLFLGASLLTIIEIVYLC 685
-*
T28D9.7 - -
SNase: domain 1 of 1, from 763 to 771: score 4.1, E = 7.6
*->kkrkGLWsd<-*
k+rk++W++
T28D9.7 763 KRRKNIWAQ 771