Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/W02B9.1a
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Query: W02B9.1a CE25133 locus:hmr-1 Cadherin, Laminin G domain status:Confirmed TR:O44327 protein_id:CAB61036.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
laminin_G Laminin G domain 70.9 6.9e-19 2
cadherin Cadherin domain 44.3 1.4e-11 1
EGF EGF-like domain 17.9 0.0024 3
Cadherin_C_term Cadherin cytoplasmic region 10.7 0.064 1
EFG_C Elongation factor G C-terminus 4.7 5.1 1
PKD PKD domain 3.6 6.1 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
cadherin 1/1 82 166 .. 5 107 .] 44.3 1.4e-11
EFG_C 1/1 248 263 .. 78 93 .] 4.7 5.1
PKD 1/1 354 378 .. 74 99 .] 3.6 6.1
EGF 1/3 553 585 .. 1 45 [] 18.5 0.0016
laminin_G 1/2 615 767 .. 1 155 [] 66.9 8.9e-18
EGF 2/3 788 829 .. 1 45 [] 8.1 1.4
laminin_G 2/2 972 993 .. 134 155 .] 3.9 7.6
EGF 3/3 1026 1054 .. 1 34 [. 6.9 3
Cadherin_C_term 1/1 1122 1205 .. 21 112 .. 10.7 0.064
Alignments of top-scoring domains:
cadherin: domain 1 of 1, from 82 to 166: score 44.3, E = 1.4e-11
*->vpEnapvGtevltvtAtDaDdPlgpNgrirYsilggnp.ggwFrIdp
++E++pvGt + t++A+D+ p + +++i +++ ++++F+Id+
W02B9.1a 82 ISEDTPVGTVLETFKAHDPS---NPMYNFSFRINRQSDpKRQFTIDQ 125
dtGdnegiisttkpLDREeifngeYeLtveAtDadpllasgggpplssta
+G+ ++++ LDRE i Y+L++eA D++ + ++
W02B9.1a 126 -DGT----LRVAHTLDREDI--AVYNLIIEAYDNS---------NNIGRQ 159
tvtitVl<-*
+v + ++
W02B9.1a 160 MVAVYLQ 166
EFG_C: domain 1 of 1, from 248 to 263: score 4.7, E = 5.1
*->eFdhYepvpgviadel<-*
eFd+ +pvpg i++++
W02B9.1a 248 EFDREAPVPGKILEIP 263
PKD: domain 1 of 1, from 354 to 378: score 3.6, E = 6.1
*->pGtYtVtLtvsNgvgsasattttvtV<-*
+GtYt + +v +++ a +vtV
W02B9.1a 354 AGTYTMSANVHDNARDEDAV-GYVTV 378
EGF: domain 1 of 3, from 553 to 585: score 18.5, E = 0.0016
*->CapnnpCsngGtCvntpggssdnfggytCeCppGdyylsytGkrC<-
C+ C+n+G+C+nt g++CeC + + G rC
W02B9.1a 553 CQHS-LCHNDGVCHNTNP-------GFFCECRND----GLKGARC 585
*
W02B9.1a - -
laminin_G: domain 1 of 2, from 615 to 767: score 66.9, E = 8.9e-18
*->FRTtepsGlLllgYnGtntdrrgkkeig.dDFlaleLvdGrlevsyd
F Tt++++lL+ YnG + r i D++ ++L++Gr+ + ++
W02B9.1a 615 FMTTQSDALLF--YNGPLETLRNDTHIEySDYIFIQLRGGRISLEVS 659
lGsghrlrpavvrsgdrvlnDGkWHrvelerngrkgtLsVdgeeps....
+ + ++ ++ + lnDG+WH ++++ +g+++ L Vd+++ + + +
W02B9.1a 660 MNGQ---SRSSLEVASTALNDGTWHDISVNQEGKRVELVVDNCR-Flgag 705
..vvdgespsgpditsenLdldtppiLyvGGlPelqksvkrrlaaists.
++++ ++++ + ++e L+ +tp + +GGl s + +++ i +++
W02B9.1a 706 adDSSCRAELYTPDDDERLNIVTP--VQIGGLA--PLSGQDYPQTIPRAg 751
FkGCirdvsingkpld<-*
+ GC+r++ +ng ++d
W02B9.1a 752 LNGCVRNLNVNGDQYD 767
EGF: domain 2 of 3, from 788 to 829: score 8.1, E = 1.4
*->Capnn.....pCsngGtCvntpggs.sdnfggytCeCppGdyylsyt
C++n ++ + C + G C +gs+ +C+C pG +
W02B9.1a 788 CDSNSvdslnHCIH-GDCFADVQGSgA---MVAKCVCDPG-----WG 825
GkrC<-*
G rC
W02B9.1a 826 GARC 829
laminin_G: domain 2 of 2, from 972 to 993: score 3.9, E = 7.6
*->aaistsFkGCirdvsingkpld<-*
+ ++++F GCi+ ++++++l
W02B9.1a 972 QGQNKGFQGCIGTYRWSKQNLP 993
EGF: domain 3 of 3, from 1026 to 1054: score 6.9, E = 3
*->Capnn..pCsngGtCvntpggssdnfggytCeCppG<-*
Ca+++ ++C + +Cv+ + g++C+C G
W02B9.1a 1026 CADLPagYCGGSFVCVDFWK-------GPFCTCNDG 1054
Cadherin_C_term: domain 1 of 1, from 1122 to 1205: score 10.7, E = 0.064
*->ReNiinYDDEGGGEeDtdAYDisaLrsggnprpieelklRrDikpev
R+N Y EGGGE D d Y ++ Lr +p l++ + ++
W02B9.1a 1122 RDNLRQYGVEGGGEADNDQYSMAGLR-----KPVMPLDTGMGPAI-G 1162
qslPRyrprptaPdnvdigdFInekLkeADnDPtAPPYDSLltYa<-*
++P+y+pr aP + +n k+k +D +A PYD L++Y+
W02B9.1a 1163 GHPPHYPPRGMAPP--KDDHELNSKIKDLETDQNAAPYDELRIYD 1205