Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm5/seq/W09C2.3
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Query:  W09C2.3  CE25154  locus:mca-1 E1-E2 ATPases (2 domains) status:Confirmed TR:O45215 protein_id:CAB61039.1

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N
--------        -----------                             -----    ------- ---
E1-E2_ATPase    E1-E2 ATPase                            134.6    6.9e-40   1
Cation_ATPase_C Cation transporting ATPase, C-terminu   102.3    5.6e-30   1
Cation_ATPase_N Cation transporter/ATPase, N-terminus    49.9    8.7e-13   1
Hydrolase       haloacid dehalogenase-like hydrolase     45.2      6e-11   2
HHE             Domain of Unknown function               12.1      0.049   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
HHE               1/1      33    71 ..     1    43 [.    12.1    0.049
Cation_ATPase_N   1/1      32   115 ..     1    87 []    49.9  8.7e-13
E1-E2_ATPase      1/1     201   445 ..    37   245 .]   134.6  6.9e-40
Hydrolase         1/2     449   472 ..     1    25 [.     3.7      9.6
Hydrolase         2/2     685   819 ..    73   184 .]    41.0    8e-10
Cation_ATPase_C   1/1     915  1066 ..     1   196 []   102.3  5.6e-30

Alignments of top-scoring domains:
HHE: domain 1 of 1, from 33 to 71: score 12.1, E = 0.049
                   *->eiidvleeeHrrlrelleelraeleealelaegadsdlldklr<-*
                      e i +l++eH+ ++ l+++l+   + +l  ++g ++dl d+ r
     W09C2.3    33    EAIVRLSTEHEGVEGLCKKLK---TDSLVGLNGEQADL-DRRR    71

Cation_ATPase_N: domain 1 of 1, from 32 to 115: score 49.9, E = 8.7e-13
                   *->eelkkevdldahkltvEevlerLktdpeeGLsseea.aeRlk.kyGp
                       e    ++  +h+ +vE ++++Lktd   GL+ e+a+ +R++++yG
     W09C2.3    32    AEAIVRLS-TEHE-GVEGLCKKLKTDSLVGLNGEQAdLDRRRhVYGA 76

                   NeLppekktslwlkfLeQFkdplvllLlaAAiiSALdfvlyg<-*
                   N++pp k++ +  ++L++ kdp++ +L ++ +i    ++l
     W09C2.3    77 NTIPPAKSKGFVRLVLDACKDPTLVILVLSGFIN---LALSF    115

E1-E2_ATPase: domain 1 of 1, from 201 to 445: score 134.6, E = 6.9e-40
                   *->VlRdGgkeeeipaeeLvpGDiVevkpGdrVPADgrvvegestLkVDE
                      V+R+G + +++p+++Lv+GDi +vk Gd  PADg ++++++ Lk+DE
     W09C2.3   201    VIRNG-EAIDVPVSDLVVGDIARVKYGDLLPADGFLIQSND-LKIDE 245

                   SaLTGESlPVeKhsdvvtpdnplergnmVfaGTlvvsGsltgvVtatGdd
                   S+LTGES    K           e +  + +GT   +Gs+++ +ta+G +
     W09C2.3   246 SSLTGESDHIKKSI---------ESDPVLLSGTYAMEGSGKMLITAVGVN 286

                   TflgkIakLVeeAqsskt................................
                   ++ g I++L      +  ++++++++++++++++++++++++++++++++
     W09C2.3   287 SQTGIIMTLLGAGKAGIGdddststsssssssssssgsssngssdssksg 336

                   ........PlQrlldkfgkiltpvililavlvfiiwllr..........n
                   +++ + ++ lQ++l k++ +++++  ++a++++i+ + r   ++   ++n
     W09C2.3   337 dddltaksVLQAKLSKLALQIIYCGTTIAIIALIVLVTRfcldhyvfekN 386

                   fn.aafggswlegllyalifavallVaAcPegLplvvtvalalGtgrmAk
                    ++ +   +++      +i+av++lV+++PegLpl++ +al+ ++++m +
     W09C2.3   387 EFsLVDIQMFVK----FFIIAVTILVISIPEGLPLAIALALTYSVRKMMH 432

                   kgaLVKglpAvEt<-*
                    + LV++l+A Et
     W09C2.3   433 DNNLVRHLDACET    445

Hydrolase: domain 1 of 2, from 449 to 472: score 3.7, E = 9.6
                   *->ikavvFDkDGTLtdgkeppiaeaiv<-*
                         ++ Dk+GTLt+  +  +++ ++
     W09C2.3   449    ATSICSDKTGTLTTN-RMTVVQSYI    472

Hydrolase: domain 2 of 2, from 685 to 819: score 41.0, E = 8e-10
                   *->dklypgarealkaLkerGikvailTngdr.naeallealgla.lfda
                      d+++p+++ a+ ++k++Gi v ++T+++  +a+a      +a  + +
     W09C2.3   685    DPVRPEVPVAISKCKKAGITVRMVTGDNImTARA------IAmSCKI 725

                   iidsddvggvgpivvgKPkpeifllalerlgvkpeevg............
                   ++ ++d +          +++ f + ++  ++k+++++ ++  ++ +
     W09C2.3   726 LEPGEDFL--------ALEGKEFNERIRDENGKVSQAKldeiwprlrvla 767

                   ......................pe.vlmvGDginDapalaaAGvgvamgn
                   + ++ ++ +  ++  +++ +++ e v++ GDg nD pal++A+vg+amg
     W09C2.3   768 raqpadkytlvkgiidskatpqREiVAVTGDGTNDGPALKKADVGFAMGI 817

                   gg<-*
                   +g
     W09C2.3   818 AG    819

Cation_ATPase_C: domain 1 of 1, from 915 to 1066: score 102.3, E = 5.6e-30
                   *->RpPRnpkkDeliftgllffrylviGvivavatlaaFvwwfygggenG
                      R+P+ +k      + l++++++++++++a+++l++ +++f++g
     W09C2.3   915    RKPYGRK------KSLISRTMVKNILCHALYQLIIIFVIFFYG---- 951

                   edfgPhllygqlshwescgantdsfkgqewCeifrkglearaqTmaFtvl
                    d+  ++  g+ ++++++                    ++++ T++F+ +
     W09C2.3   952 -DTIFGIKTGLYAPLFAP--------------------PSQHFTLVFNAF 980

                   VviqmfNAWEalncrsefFmhpldrnSlfqmgpgLfrNkwLllAvvlsla
                   V++  fN   ++n+r       ++ +   +++ gL +N+++++++v +++
     W09C2.3   981 VMMTVFN---EINARK------VHGE--RNVFKGLASNRVFCVIWVTTFI 1019

                   lqllivYvPglqtiFgthpllslqeW.vvigfsflvfildElrKfikRrr
                    q++iv ++g ++++   pl +lq+W v+++++f+ +i++ +   i+ ++
     W09C2.3  1020 AQIIIVQFGGAWFSTA--PL-TLQQWiVCLVLGFSTLIWGQIVATIPSKK 1066

                   <-*

     W09C2.3     -     -



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