Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/W09C2.3
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: W09C2.3 CE25154 locus:mca-1 E1-E2 ATPases (2 domains) status:Confirmed TR:O45215 protein_id:CAB61039.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
E1-E2_ATPase E1-E2 ATPase 134.6 6.9e-40 1
Cation_ATPase_C Cation transporting ATPase, C-terminu 102.3 5.6e-30 1
Cation_ATPase_N Cation transporter/ATPase, N-terminus 49.9 8.7e-13 1
Hydrolase haloacid dehalogenase-like hydrolase 45.2 6e-11 2
HHE Domain of Unknown function 12.1 0.049 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
HHE 1/1 33 71 .. 1 43 [. 12.1 0.049
Cation_ATPase_N 1/1 32 115 .. 1 87 [] 49.9 8.7e-13
E1-E2_ATPase 1/1 201 445 .. 37 245 .] 134.6 6.9e-40
Hydrolase 1/2 449 472 .. 1 25 [. 3.7 9.6
Hydrolase 2/2 685 819 .. 73 184 .] 41.0 8e-10
Cation_ATPase_C 1/1 915 1066 .. 1 196 [] 102.3 5.6e-30
Alignments of top-scoring domains:
HHE: domain 1 of 1, from 33 to 71: score 12.1, E = 0.049
*->eiidvleeeHrrlrelleelraeleealelaegadsdlldklr<-*
e i +l++eH+ ++ l+++l+ + +l ++g ++dl d+ r
W09C2.3 33 EAIVRLSTEHEGVEGLCKKLK---TDSLVGLNGEQADL-DRRR 71
Cation_ATPase_N: domain 1 of 1, from 32 to 115: score 49.9, E = 8.7e-13
*->eelkkevdldahkltvEevlerLktdpeeGLsseea.aeRlk.kyGp
e ++ +h+ +vE ++++Lktd GL+ e+a+ +R++++yG
W09C2.3 32 AEAIVRLS-TEHE-GVEGLCKKLKTDSLVGLNGEQAdLDRRRhVYGA 76
NeLppekktslwlkfLeQFkdplvllLlaAAiiSALdfvlyg<-*
N++pp k++ + ++L++ kdp++ +L ++ +i ++l
W09C2.3 77 NTIPPAKSKGFVRLVLDACKDPTLVILVLSGFIN---LALSF 115
E1-E2_ATPase: domain 1 of 1, from 201 to 445: score 134.6, E = 6.9e-40
*->VlRdGgkeeeipaeeLvpGDiVevkpGdrVPADgrvvegestLkVDE
V+R+G + +++p+++Lv+GDi +vk Gd PADg ++++++ Lk+DE
W09C2.3 201 VIRNG-EAIDVPVSDLVVGDIARVKYGDLLPADGFLIQSND-LKIDE 245
SaLTGESlPVeKhsdvvtpdnplergnmVfaGTlvvsGsltgvVtatGdd
S+LTGES K e + + +GT +Gs+++ +ta+G +
W09C2.3 246 SSLTGESDHIKKSI---------ESDPVLLSGTYAMEGSGKMLITAVGVN 286
TflgkIakLVeeAqsskt................................
++ g I++L + ++++++++++++++++++++++++++++++++
W09C2.3 287 SQTGIIMTLLGAGKAGIGdddststsssssssssssgsssngssdssksg 336
........PlQrlldkfgkiltpvililavlvfiiwllr..........n
+++ + ++ lQ++l k++ +++++ ++a++++i+ + r ++ ++n
W09C2.3 337 dddltaksVLQAKLSKLALQIIYCGTTIAIIALIVLVTRfcldhyvfekN 386
fn.aafggswlegllyalifavallVaAcPegLplvvtvalalGtgrmAk
++ + +++ +i+av++lV+++PegLpl++ +al+ ++++m +
W09C2.3 387 EFsLVDIQMFVK----FFIIAVTILVISIPEGLPLAIALALTYSVRKMMH 432
kgaLVKglpAvEt<-*
+ LV++l+A Et
W09C2.3 433 DNNLVRHLDACET 445
Hydrolase: domain 1 of 2, from 449 to 472: score 3.7, E = 9.6
*->ikavvFDkDGTLtdgkeppiaeaiv<-*
++ Dk+GTLt+ + +++ ++
W09C2.3 449 ATSICSDKTGTLTTN-RMTVVQSYI 472
Hydrolase: domain 2 of 2, from 685 to 819: score 41.0, E = 8e-10
*->dklypgarealkaLkerGikvailTngdr.naeallealgla.lfda
d+++p+++ a+ ++k++Gi v ++T+++ +a+a +a + +
W09C2.3 685 DPVRPEVPVAISKCKKAGITVRMVTGDNImTARA------IAmSCKI 725
iidsddvggvgpivvgKPkpeifllalerlgvkpeevg............
++ ++d + +++ f + ++ ++k+++++ ++ ++ +
W09C2.3 726 LEPGEDFL--------ALEGKEFNERIRDENGKVSQAKldeiwprlrvla 767
......................pe.vlmvGDginDapalaaAGvgvamgn
+ ++ ++ + ++ +++ +++ e v++ GDg nD pal++A+vg+amg
W09C2.3 768 raqpadkytlvkgiidskatpqREiVAVTGDGTNDGPALKKADVGFAMGI 817
gg<-*
+g
W09C2.3 818 AG 819
Cation_ATPase_C: domain 1 of 1, from 915 to 1066: score 102.3, E = 5.6e-30
*->RpPRnpkkDeliftgllffrylviGvivavatlaaFvwwfygggenG
R+P+ +k + l++++++++++++a+++l++ +++f++g
W09C2.3 915 RKPYGRK------KSLISRTMVKNILCHALYQLIIIFVIFFYG---- 951
edfgPhllygqlshwescgantdsfkgqewCeifrkglearaqTmaFtvl
d+ ++ g+ ++++++ ++++ T++F+ +
W09C2.3 952 -DTIFGIKTGLYAPLFAP--------------------PSQHFTLVFNAF 980
VviqmfNAWEalncrsefFmhpldrnSlfqmgpgLfrNkwLllAvvlsla
V++ fN ++n+r ++ + +++ gL +N+++++++v +++
W09C2.3 981 VMMTVFN---EINARK------VHGE--RNVFKGLASNRVFCVIWVTTFI 1019
lqllivYvPglqtiFgthpllslqeW.vvigfsflvfildElrKfikRrr
q++iv ++g ++++ pl +lq+W v+++++f+ +i++ + i+ ++
W09C2.3 1020 AQIIIVQFGGAWFSTA--PL-TLQQWiVCLVLGFSTLIWGQIVATIPSKK 1066
<-*
W09C2.3 - -