Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm5/seq/Y18D10A.9
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Query:  Y18D10A.9  CE21405   WD domain, G-beta repeat status:Partially_confirmed TR:Q9XW12 protein_id:CAA22322.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
WD40     WD domain, G-beta repeat                       153.3    4.1e-42   6

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
WD40       1/6      17    45 ..    10    39 .]    23.0  9.9e-05
WD40       2/6      57    95 ..     1    39 []    25.7  1.7e-05
WD40       3/6     101   139 ..     1    39 []    33.9  7.5e-08
WD40       4/6     146   184 ..     1    39 []    30.9  5.6e-07
WD40       5/6     234   260 ..    12    39 .]    18.3   0.0021
WD40       6/6     270   311 ..     1    39 []    35.6  2.5e-08

Alignments of top-scoring domains:
WD40: domain 1 of 6, from 17 to 45: score 23.0, E = 9.9e-05
                   *->tspvtcvafspdsgpylasgSrDgtiklWd<-*
                      ts v+  ++++  g++las+++D+ +++W+
   Y18D10A.9    17    TSRVWMTCWHHG-GRILASCGDDKAVRVWS    45

WD40: domain 2 of 6, from 57 to 95: score 25.7, E = 1.7e-05
                   *->geclatl.gHtspvtcvafspdsgpylasgSrDgtiklWd<-*
                       + ++  + Ht +v++vafs d g++l+s+S D ++ ++
   Y18D10A.9    57    ECRTTLDdSHTRAVRSVAFSND-GKCLVSASFDASVVVYQ    95

WD40: domain 3 of 6, from 101 to 139: score 33.9, E = 7.5e-08
                   *->geclatl.gHtspvtcvafspdsgpylasgSrDgtiklWd<-*
                         +  l+gH+s v c  fs +  ++la++SrD+++  W
   Y18D10A.9   101    FAEVNKLeGHESEVKCAVFSKS-DEFLATCSRDKSVWFWQ    139

WD40: domain 4 of 6, from 146 to 184: score 30.9, E = 5.6e-07
                   *->geclatl.gHtspvtcvafspdsgpylasgSrDgtiklWd<-*
                       ++ ++l+ Ht  v  va++p    +l+s+S D +i+ +
   Y18D10A.9   146    FSVSSILqPHTQDVKQVAWHPT-EDLLVSCSYDSSIRFYR    184

WD40: domain 5 of 6, from 234 to 260: score 18.3, E = 0.0021
                   *->pvtcvafspdsgpylasgSrDgtiklWd<-*
                      p ++va++     ++a+g+ D++i+l++
   Y18D10A.9   234    PLYSVAWNST-NDVIATGGGDCKIRLFK    260

WD40: domain 6 of 6, from 270 to 311: score 35.6, E = 2.5e-08
                   *->geclatl.gHtspvtcvafspd..sgpylasgSrDgtiklWd<-*
                       e l + + H+  v+ va++p+++ +++l s+S+Dgti+lW+
   Y18D10A.9   270    IEHLGVVgRHELDVNHVAWNPNpkFSNLLTSASDDGTIRLWE    311



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