Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/Y32H12A.8
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Query: Y32H12A.8 CE28516 status:Partially_confirmed TR:Q9N533 protein_id:AAF60491.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
WD40 WD domain, G-beta repeat 73.1 5.4e-19 5
DUF6 Integral membrane protein DUF6 9.9 0.39 1
zf-Sec23_Sec24 Sec23/Sec24 zinc finger 6.9 3.4 1
DUF408 Domain of Unknown Function (DUF408) 3.2 8.8 1
Pyrophosphatase Inorganic pyrophosphatase 3.0 8.9 1
integrin_B Integrin, beta chain 0.8 5.3 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
WD40 1/5 108 131 .. 16 39 .] 12.4 0.1
WD40 2/5 134 173 .. 1 39 [] 34.6 4.8e-08
WD40 3/5 179 220 .. 1 39 [] 5.2 11
WD40 4/5 225 265 .. 1 39 [] 14.5 0.025
WD40 5/5 316 355 .. 1 39 [] 15.1 0.017
DUF6 1/1 700 724 .. 1 25 [. 9.9 0.39
integrin_B 1/1 797 807 .. 431 441 .] 0.8 5.3
zf-Sec23_Sec24 1/1 793 817 .. 18 42 .] 6.9 3.4
Pyrophosphatase 1/1 2920 2943 .. 163 187 .] 3.0 8.9
DUF408 1/1 2944 2961 .. 80 97 .. 3.2 8.8
Alignments of top-scoring domains:
WD40: domain 1 of 5, from 108 to 131: score 12.4, E = 0.1
*->vafspdsgpylasgSrDgtiklWd<-*
v++++ + +y+a+ S++g+i W+
Y32H12A.8 108 VKWNQLYDQYIATTSSNGSIVCWN 131
WD40: domain 2 of 5, from 134 to 173: score 34.6, E = 4.8e-08
*->geclatl.gHtspvtcvafspdsgpylasgSrDgtiklWd<-*
+ +++++ H+ + tc++++ + +l+sgSrD+t+k +d
Y32H12A.8 134 RRNKSVFkSHERSATCLDWHATTPYILVSGSRDCTVKSYD 173
WD40: domain 3 of 5, from 179 to 220: score 5.2, E = 11
*->geclatl.gHtspvtcvafspd..sgpylasgSrDgtiklWd<-*
+l+ + ++++va + ++ y+++g + g ++lWd
Y32H12A.8 179 NHQLTFSdRNCESIRDVAMCKApgFDDYFFTGDDGGVLRLWD 220
WD40: domain 4 of 5, from 225 to 265: score 14.5, E = 0.025
*->geclatl.gHtspvtcvafspdsgpylas.gSrDgtiklWd<-*
+ + +H s+v+ ++ +p++++++a++g+rD+ +k+W+
Y32H12A.8 225 RRWVFQKvAHRSFVSTLSLNPHNRTLIATgGGRDKMVKIWE 265
WD40: domain 5 of 5, from 316 to 355: score 15.1, E = 0.017
*->geclatl.gHtspvtcvafspdsgpylasgSrDgtiklWd<-*
+ t++ H ++vt+ ++ + ++ +++ Dg + l +
Y32H12A.8 316 YLPYVTYdEHRDSVTDACWPSTDFDVFMTCGKDGLVVLHN 355
DUF6: domain 1 of 1, from 700 to 724: score 9.9, E = 0.39
*->fiWalytvfskkllerispltftaw<-*
++a++ v++k+ll ++p+t+++w
Y32H12A.8 700 TCAAISMVCGKRLLDAVDPYTVNGW 724
integrin_B: domain 1 of 1, from 797 to 807: score 0.8, E = 5.3
*->evqvhfiCdvC<-*
+v+ +f+C+vC
Y32H12A.8 797 IVGMTFQCNVC 807
zf-Sec23_Sec24: domain 1 of 1, from 793 to 817: score 6.9, E = 3.4
*->cqfddrarrWqCnfCgsrNdvPpeY<-*
c+f + ++ +qCn Cg+ ++ +Y
Y32H12A.8 793 CRFGIVGMTFQCNVCGHCMHTDHAY 817
Pyrophosphatase: domain 1 of 1, from 2920 to 2943: score 3.0, E = 8.9
*->kvsgwgKdkneAkdvIresidrwka<-*
+v++ + dk+ A+++ r ++drw+
Y32H12A.8 2920 AVEAQRRDKK-AEEAARRCMDRWEV 2943
DUF408: domain 1 of 1, from 2944 to 2961: score 3.2, E = 8.8
*->ikrkqkYkIsrKenKVYd<-*
i r q+++I++Ke K+ d
Y32H12A.8 2944 IEREQRWEIEDKERKIHD 2961
[output cut off at A = 10 top alignments]