Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/Y39A1A.19
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Query: Y39A1A.19 CE19139 DIMETHYLANILINE MONOOXYGENASE (N-OXIDE FORMING) 5 (EC 1.14.13.8) (HEPATIC FLAVIN-CONTAINING MONOOXYGENASE 5) (FMO 5)
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
FMO-like Flavin-binding monooxygenase-like 542.7 2.6e-159 1
pyr_redox Pyridine nucleotide-disulphide oxidore 24.6 2.5e-06 2
DAO FAD dependent oxidoreductase 4.7 2.5 1
Glycoprotein_B Herpesvirus Glycoprotein B 1.0 6.4 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DAO 1/1 6 18 .. 1 13 [. 4.7 2.5
pyr_redox 1/2 7 43 .. 1 47 [. 10.6 0.027
pyr_redox 2/2 110 230 .. 99 213 .. 14.0 0.0029
Glycoprotein_B 1/1 358 372 .. 742 756 .] 1.0 6.4
FMO-like 1/1 5 493 .. 1 489 [. 542.7 2.6e-159
Alignments of top-scoring domains:
DAO: domain 1 of 1, from 6 to 18: score 4.7, E = 2.5
*->mdvvVIGgGViGl<-*
++++V+G+G++Gl
Y39A1A.19 6 KQLLVVGAGASGL 18
pyr_redox: domain 1 of 2, from 7 to 43: score 10.6, E = 0.027
*->dvvIIGgGpAGlaAAiraaragflGrkrlkvalvEkepplkrgtlGG
+++++G+G+ Gl ++a + + +v+++Ek + ++GG
Y39A1A.19 7 QLLVVGAGASGLPSIRHALL--YPN---VEVTCFEKTN-----EVGG 43
<-*
Y39A1A.19 - -
pyr_redox: domain 2 of 2, from 110 to 230: score 14.0, E = 0.0029
*->gtevt.ldkknkvvi.........tvlgdgetltydkliiATGarpr
+ v+++d+++ ++++ + + ++++g+++t +d + +++G ++
Y39A1A.19 110 NNSVIsIDRNDDYDVtgkwkvrysDETGAEKTRIFDGVMLCSG-HHA 155
ippipGvpgflfaglegvfglrtsddAlalrevpkgkrvvVvGGGyIGlE
ip ip + g e ++g++t + +++ + +++k vvVvG G+ G +
Y39A1A.19 156 IPHIPK--P--WPGQEKFKGRITHSHDYKDHKGYEDKTVVVVGIGNSGGD 201
lAaalarlGaeVTvverrd.rllprkdde<-*
lA +l+r+ ++V++v rr +++ r +d+
Y39A1A.19 202 LAVELSRISKQVYLVTRRGsWIFNRLFDR 230
Glycoprotein_B: domain 1 of 1, from 358 to 372: score 1.0, E = 6.4
*->kaLYPyttkalktva<-*
k+++P++t +++t a
Y39A1A.19 358 KYMFPMATADKNTLA 372
FMO-like: domain 1 of 1, from 5 to 493: score 542.7, E = 2.6e-159
*->aKkVAVIGAGVSGLaSiK.CCLeEGILEPtCFERSdDIGGLWrFtEn
+K V+GAG SGL Si++ +L E+tCFE+++ +GGLW +
Y39A1A.19 5 KKQLLVVGAGASGLPSIRhALLYPN-VEVTCFEKTNEVGGLWNYKPY 50
vEeGrASiYKSvvtNvsKEMsCYSDFPfPedy.PNFmhnskilEYLrmfA
e + KS v+N+sKEM +SDFP Ped+ NFmhn + YL +A
Y39A1A.19 51 KTELS-TVMKSTVINTSKEMTSFSDFP-PEDTmANFMHNTEMCRYLNNYA 98
keFdLLKYIQFkTtVcSVkKrPDFstsGQWeVv....TeseGKqesaVFD
k+ LLKYI F V S+ D +++G W V+ +++T e + +FD
Y39A1A.19 99 KHHELLKYIKFNNSVISIDRNDDYDVTGKWKVRysdeTGAE---KTRIFD 145
AVMVCTGhhtnPhLPLeSFPGiekFKGqyFHSrdYKhPegFlGKRVlVIG
VM C+Ghh Ph+P ++ PG ekFKG + HS dYK g ++K V+V+G
Y39A1A.19 146 GVMLCSGHHAIPHIP-KPWPGQEKFKGRITHSHDYKDHKGYEDKTVVVVG 194
lGNSGgDiAvELSrtAeqVflStRtGsWVLsRvsdrGYPwdmvfhtRFps
+GNSGgD+AvELSr +qV l tR+GsW+ +R +drG P+dm + + F+
Y39A1A.19 195 IGNSGGDLAVELSRISKQVYLVTRRGSWIFNRLFDRGEPLDMCLNSKFQM 244
flsniLptyisnwlmFekqLNnrfnHenYGLapknrslrKEPvvNDeLPn
ls p +++nw e+ LN rf+H++YGL+p + ++ + +vNDeLPn
Y39A1A.19 245 WLSETIPFPLVNWNF-ERLLNMRFDHAKYGLKPNHPAMGAHITVNDELPN 293
RILtGaVkvkpsVKeltEtSAiFeDGtveEdIDvViFATGYtFsFPFLeE
RI G V vkp +K +tEtS FeDGt E++D Vi ATG++F+F e
Y39A1A.19 294 RIASGTVRVKPGIKSFTETSIHFEDGTFVENVDEVILATGFSFHFNLIEN 343
.slVkvevnkvsLYKyvFP.phLekpTLaiiGLIqplGsiiptvelQaRW
+ lVkv nk +Ky+FP + + k TLa+iGL+q Gsi+p++e QaR
Y39A1A.19 344 gNLVKVDENKTDAFKYMFPmATADKNTLAVIGLVQVIGSIMPISEMQARV 393
AvqVfKGlckLPsfskMmeeItekkEkkikrfGnsqltavqtDYIeYmde
f+ LPs ++M +++k + + r+++s ++++q D Y+ e
Y39A1A.19 394 YLESFAAGRELPSKEEMFHNVIAKRQQMANRYVESRRHTIQVDFLPYLHE 443
lakfigaKPnlpsllLtDPkLAlevfFGPCsPyqyRLtGPGkWeGARnAI
l + ig P+ l + P LA+ v+FGPC Py +RL GP W GA AI
Y39A1A.19 444 LGALIGCNPDMKALWMKNPLLAWRVYFGPCVPYVFRLNGPNTWQGAEQAI 493
<-*
Y39A1A.19 - -