Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm5/seq/Y48B6A.4
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Query:  Y48B6A.4  CE22119    status:Partially_confirmed TR:Q9U298 protein_id:CAB54450.1

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N
--------       -----------                              -----    ------- ---
Neur_chan_LBD  Neurotransmitter-gated ion-channel lig   297.2      2e-85   1
Neur_chan_memb Neurotransmitter-gated ion-channel tra    82.8    1.5e-23   2

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
Neur_chan_LBD    1/1      25   234 ..     1   246 []   297.2    2e-85
Neur_chan_memb   1/2     241   353 ..     1   116 [.    62.7  1.2e-17
Neur_chan_memb   2/2     420   458 ..   253   291 .]    20.4  3.6e-05

Alignments of top-scoring domains:
Neur_chan_LBD: domain 1 of 1, from 25 to 234: score 297.2, E = 2e-85
                   *->etrLlddLlentvsgYdkrvRPv.nggdvPpvtVsvgltlqqiisVd
                      e+rLl+dL e+    Yd+ +RPv ++++ P v+V+++l lqq+++Vd
    Y48B6A.4    25    EYRLLKDLREG----YDPVERPVaDHRK-P-VNVKLRLILQQLVDVD 65

                   EknqdlttnvwlrqgqWtDpRLaWnpsdplddeddyggikslrlpsddeh
                   E+nq++t+ vw ++ +W+D++L+W p++       yg+i++l +p+
    Y48B6A.4    66 ERNQVITLVVWNQY-TWNDYKLRWSPEE-------YGNITTLQIPHG--- 104

                   dmldkIWlPDiflyNqttskadgnhdvttpntnvrvypglkdGtVlwspp
                        +W+PDi+l+N    +a + +d + + ++++v++   +G+Vl  pp
    Y48B6A.4   105 ----TLWKPDILLFN----SANEHFDAS-FPVHMVVSS---NGDVLFAPP 142

                   aiykssCpmdltyFPFDqQnCslkFgSwtYngdevdlqwkdd....leei
                   +i++ sC++ +t+FP+DqQ C+lkFgSwtY g+++dlq +d + ++ +++
    Y48B6A.4   143 GIVSFSCSLSMTWFPYDQQVCYLKFGSWTY-GKKLDLQIDDSdlpdGHKM 191

                   dLpdFtengeWdlldvpakrnekpygcyselsgagLnklvYpditfyfvl
                   dL+ +++nge dll +pa r  k++   +e          Y++++f+ +l
    Y48B6A.4   192 DLQYYIPNGEFDLLATPAFR--KSTTFLDET---------YVELYFHMHL 230

                   rRkp<-*
                   +R++
    Y48B6A.4   231 KRRT    234

Neur_chan_memb: domain 1 of 2, from 241 to 353: score 62.7, E = 1.2e-17
                   *->liiPCvLIsfLswLvFyLPsDaGPeKvtLgIsvLLtlTvFlllirei
                       i+P++LIs   +L F  P+++G eK+tL I+  L+  vFl  ++e
    Y48B6A.4   241    WIVPSILISLSNILGFTMPPECG-EKITLQITNFLSVMVFLAMVSEV 286

                   lPkTSlvvPLigkYllFtMfvvtasieyavvvlnvhhRsPkstHkmpewv
                    P+TS ++P+i  ++   ++   +si  + ++ n+++R P +tH+m +w
    Y48B6A.4   287 APPTSESIPIIAAFFSLSIVILGLSICASLIIVNIFFRHP-KTHRMGDWT 335

                   rklfLerklPrllfmkrpn<-*
                   r +fL ++lP++l+m+rp+
    Y48B6A.4   336 RYVFL-EWLPWFLLMSRPE    353

Neur_chan_memb: domain 2 of 2, from 420 to 458: score 20.4, E = 3.6e-05
                   *->skdeddsvkedWkyvamvIDRlflwiFpivfvlGTlgyf<-*
                      ++ e++++  +W ++amvIDRl+l++F+ +    T+ +f
    Y48B6A.4   420    DDEEEEEEILNWRFMAMVIDRLSLFLFTGLIFGTTALIF    458



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