Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/Y48B6A.7
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Query: Y48B6A.7 CE26734 locus:ace-4 acetylcholinesterase status:Confirmed TR:O61372 protein_id:CAB54444.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
COesterase Carboxylesterase 651.8 3.7e-192 1
DUF621 Protein of unknown function (DUF621) 3.4 8.5 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DUF621 1/1 41 48 .. 138 145 .] 3.4 8.5
COesterase 1/1 1 562 [. 1 592 [] 651.8 3.7e-192
Alignments of top-scoring domains:
DUF621: domain 1 of 1, from 41 to 48: score 3.4, E = 8.5
*->fFFTSkeI<-*
fFF+Sk+I
Y48B6A.7 41 FFFLSKKI 48
COesterase: domain 1 of 1, from 1 to 562: score 651.8, E = 3.7e-192
*->mglllllllllllllavvataptspedp.vVeTsyvgGkvrGlrvkv
m+ +l ++++++ ++ ++++ +p v+eT++ G ++G+ +
Y48B6A.7 1 MKPKLAFFAFFIFITVFIDSVQAV--HPvVLETKL--GDIKGTEFFF 43
dggnkpvyaFlGIPYAkPPvGeLRFkkPqPipepWtgvldATkygpaCpQ
k++++F G+P+A+P v + RF+kP+ ++ W g +dATk+++aC+Q
Y48B6A.7 44 LS--KKIRTFFGVPFAEPAVEDFRFRKPRE-KKQWRGLYDATKPANACFQ 90
.ndlgfpgfpLAlevmgsemwnkntgvsmSEDCLYLNVytPklasenkkl
++d +++ f+ gsemwn+nt +SEDCLYLN+++P++a n l
Y48B6A.7 91 tRDNYNTSFW------GSEMWNANTQ--ISEDCLYLNIWAPADAY-N--L 129
PVmVwIHGGGFqsGsassfslddydgpdlaaekdVVVVtiNYRLGalGFL
+VmVw++GGGF+sGs+ sl++ydg+ l ++++V+VV+iNYRLG++GFL
Y48B6A.7 130 TVMVWFFGGGFYSGSP---SLSIYDGKALTSTQNVIVVNINYRLGPFGFL 176
stgdselpvppGNaGLlDQvlALrWVqeNIaaFGGDPdnVTlFGeSAGAa
++g +++p GN+GLlDQ+lAL+WV++NI +FGG+Pd+V +FG+SAGAa
Y48B6A.7 177 YLGHPDAP---GNMGLLDQQLALHWVRQNIVSFGGNPDKVAVFGQSAGAA 223
SVsllllSppqsrgLFhrAIlqSGsalspwaits.pearnrakrlAkllG
S+ ++l++ p srgLF+ AIlqSGs + wai+s+ +a +++++l +l+G
Y48B6A.7 224 SIVAHLIA-PGSRGLFKNAILQSGSLENTWAINSpFRAKQKSEKLLELVG 272
CpgedstelleCLRkksaeelldaqeklllldevgffpffaFgPvvdGdt
C+++++++ ++CLR +s+e+l ++ + + fp F+ v +
Y48B6A.7 273 CNKTTVDTSMACLRLVSPEQLSLSTW--NISLTYLEFP---FVIVSRDK- 316
pdaflpkdPeellkegnfn.kvPlliGvtsdEGllflayll.dp.esadl
++f + d +l+eg+fn++v+l+iG+++dEG ++ y+l+++ ++ad+
Y48B6A.7 317 -HFFGHLDAHAALREGDFNrDVNLMIGMNKDEGNYWNIYQLpQFfDKADP 365
lslldned.............lflellpellpgaselltpklreeiadal
+l+ e++ +++ + ++++ ++ ++++ ++ + +
Y48B6A.7 366 PELNRTEFdflidrtfsiqpdIIRSAAKYIYSDPNCTD--------HGRK 407
keeYtdd.ddnseesr.ealvdllsDylFvcpilrlaaarlakggapvYl
+Y + +++ +++ + + l D + +p r+ +++ ++ + +v++
Y48B6A.7 408 TRFYAGQmNQIVGDYFfSCDSLWLADQFRSIP--RVKSSSPQRKPGKVFV 455
YrFdyrssfsfnqylinllwppwmgvsHgdelsYvFGnpls.k.lyteee
Y+F++ ss +++wp+w+g++Hg+e++YvFG pls +++y+ +e
Y48B6A.7 456 YHFTQSSS--------ANPWPKWTGAMHGYEIEYVFGIPLSySkNYKRRE 497
eklssrrmmrywtnFAktGnPNngessglpkWppytseeqkYyllntllt
+ +sr++m++w++FAk+G P + + +Wp++++ + y +l
Y48B6A.7 498 QI-FSRKIMQFWASFAKNGTPKLRVLKNSEHWPEFNEQNH--YRWMQLRS 544
istk.lreedprk.vkcafw<-*
s +++ + k+v+c+fw
Y48B6A.7 545 GSNIrPIKPK--KqVECQFW 562