Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm5/seq/Y51A2D.19b
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Query:  Y51A2D.19b  CE30365  locus:slo-1  status:Confirmed TR:Q95V26 protein_id:CAD27617.1

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N
--------      -----------                               -----    ------- ---
BK_channel_a  Calcium-activated BK potassium channel   1118.7          0   2
ion_trans     Ion transport protein                      82.4    3.4e-21   1
zf-C3HC4      Zinc finger, C3HC4 type (RING finger)      10.2       0.01   1
ABC2_membrane ABC-2 type transporter                      3.3        8.4   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
ion_trans       1/1     177   351 ..     1   228 []    82.4  3.4e-21
ABC2_membrane   1/1     331   352 ..   241   262 .]     3.3      8.4
zf-C3HC4        1/1     643   662 ..     1    24 [.    10.2     0.01
BK_channel_a    1/2     403   664 ..     1   264 [.   471.9 5.2e-138
BK_channel_a    2/2     746  1106 ..   316   687 ..   648.2 4.4e-191

Alignments of top-scoring domains:
ion_trans: domain 1 of 1, from 177 to 351: score 82.4, E = 3.4e-21
                   *->ileildyvftviFtlEmllkiialgfklhsriprkYlrspwnilDfl
                      + + +d+ f+++F++ +++++ia+  k       ++l +++ ++Df+
  Y51A2D.19b   177    PSQQIDLGFNIFFLVYFFIRFIAASDK------VWFLLEMYSWIDFF 217

                   vvlpslislilflsgggsvklirlreslflalsevsygilsvlrllRllR
                    + ps++ ++l++   g                      +++lr+lRl+
  Y51A2D.19b   218 TIPPSFVAIYLQRNWLG----------------------FRFLRALRLMT 245

                   vLRllrllrrapglfefelrtlGWklqslgrslkslfnlllllllllfif
                      +  +l+++       l+t          s++    ++++++++l +
  Y51A2D.19b   246 ---VPDILQYLNI-----LKTS--------SSIRLTQLVTIFVAVCLTGA 279

                   aiigvqlfggelnkccnpingntnFdnfgeaflwlFqtlTteGwgdimpd
                   +++ ++  +g ++k+    + n++  ++ ++++++++t++t+G+gdi+++
  Y51A2D.19b   280 GLVHLLENSGDFFKG----FINPHRITYADSVYFVLVTMSTVGYGDIYCT 325

                   tlagtvlgkiyfvifiilggflllNlfiavi<-*
                       t  g +++ if+il+g+ +++ +++ i
  Y51A2D.19b   326 ----TLCGRLFM-IFFILFGLAMFASYVPEI    351

ABC2_membrane: domain 1 of 1, from 331 to 352: score 3.3, E = 8.4
                   *->lvslillliGlliFrkfekrfa<-*
                      l+++ + l+Gl++F ++ +++a
  Y51A2D.19b   331    LFMIFFILFGLAMFASYVPEIA    352

zf-C3HC4: domain 1 of 1, from 643 to 662: score 10.2, E = 0.01
                   *->CrICleelkepsndfplilpCgHs<-*
                      C  C++  k+ s    li  C+++
  Y51A2D.19b   643    CKQCHDDIKDVS----LIKKCKCK    662

BK_channel_a: domain 1 of 2, from 403 to 664: score 471.9, E = 5.2e-138
                   *->EivFLHnisPdLELEALFKRHFtqvEFYqGsvLnPHDLARvKiEsAD
                      E+vFLH + PdLELE LFKRHFt+vEF+ G v+   DL RvKi  AD
  Y51A2D.19b   403    EVVFLHRVVPDLELEGLFKRHFTKVEFFTGTVMDSLDLSRVKIGDAD 449

                   ACLiLAnKYCADPDAEDAsnimRvisiKnYHPKiRiitqmLqYHnKAHLL
                   ACL+LAnKY   PDAEDA+nimRvisiKnY   iR+i q++qYHnKA LL
  Y51A2D.19b   450 ACLVLANKYSTNPDAEDAANIMRVISIKNYSSDIRVIVQLMQYHNKAYLL 499

                   niPsWnWKEGDDAiCLAELKLGFiAqsCLAqGLstmLAnLFsmRsFiKiE
                   niPsW WK GDD iCLAELKLGFiAqsCLA+G stm+AnLF+mRsF K
  Y51A2D.19b   500 NIPSWDWKRGDDVICLAELKLGFIAQSCLAPGFSTMMANLFAMRSF-KTS 548

                   EDt..WqKYYLEGvsnEmYtEYLssAFvGLsFPavCELvFvKLKLLmiAi
                     t++W   YL G   EmYt+ Ls  FvG+ FP   +L F +L LL++Ai
  Y51A2D.19b   549 QTTpdWLNLYLCGAGMEMYTDTLSHSFVGMTFPEAVDLLFNRLGLLLLAI 598

                   EYK.sekREsRsrkriLinPGnHlKiqEGtLGFFiAsDAKEvKRAyFYCK
                   E K+ e++E      i inPG H+ iq  t GFFiA  A EvKRA+F+CK
  Y51A2D.19b   599 ELKdEENKECN----IAINPGPHIVIQPQTQGFFIAQSADEVKRAFFWCK 644

                   Achdditdpkrikkcgckrl<-*
                    chddi d   ikkc ck l
  Y51A2D.19b   645 QCHDDIKDVSLIKKCKCKNL    664

BK_channel_a: domain 2 of 2, from 746 to 1106: score 648.2, E = 4.4e-191
                   *->KYDstGmFHWCagKeiEKviLtRsEAAmtvLsGHvvvCiFGDvksAL
                      KYDstGmFHWC+ +++E  +L R  AAmtvL GHvvvC+F D  s L
  Y51A2D.19b   746    KYDSTGMFHWCPSRNLEDCVLERHQAAMTVLNGHVVVCLFADQDSPL 792

                   iGlRnLvmPLRAsnFHYHELKHivFvGslEYLKREWEtLHnFPKvsiLPG
                   iGlRn +mPLR snFHYHELKH+v vG lEYL++EW tL n PK+siL G
  Y51A2D.19b   793 IGLRNFIMPLRSSNFHYHELKHVVIVGDLEYLRKEWKTLYNLPKISILNG 842

                   tPLsRADLRAvninlCDmCviLsAnqnniDDasLqDKECiLAsLniKsmq
                    PLsRADLRAvninlCDmCvi+sA   n +D+ L DKE iLAsLniK+mq
  Y51A2D.19b   843 SPLSRADLRAVNINLCDMCVIISARVPNTEDTTLADKEAILASLNIKAMQ 892

                   FDDsiGvLqAnsqGFtPPGmDRssPDnsPvHGlLRqPsittGvniPiitE
                   FDD +G      q       DR sP  sP+   + +     G n+P+itE
  Y51A2D.19b   893 FDDTLGFFPMRHQ-----TGDR-SPLGSPIS--MQKKGAKFGTNVPMITE 934

                   LvnDsnvqFLDqDDDDDPDtELYLtqPFACGtAFAvsvLDsLmsAtYFnD
                   LvnDsnvqFLDqDDDDDPDtELYLtqPFACGtAFA+svLDsLms tYFnD
  Y51A2D.19b   935 LVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAISVLDSLMSTTYFND 984

                   niLtLiRtLvtGrAtPELEALiAEEnALRrsYstPqtLAnRDRCrvAqLA
                     LtLiRtLvtG+AtPELE ++AE   LR++YstP tL nRDRCr+Aq+
  Y51A2D.19b   985 SALTLIRTLVTGGATPELELILAEGAGLRGGYSTPETLSNRDRCRIAQIS 1034

                   LlDGPFADLGDGGCYGDLFCKALKtYnmLCFGiYRLRDAHLstPsqCtKR
                   L D P+  +     YG +F  AL+ Y  LC G+YRL D          KR
  Y51A2D.19b  1035 LQDNPYDGVVHNTTYGAMFTIALRRYGQLCIGLYRLHDQD---NPDSMKR 1081

                   YvitnPPYEFELvPtDLiFCLmqFD<-*
                   YvitnPP E  +  tD ++ L qFD
  Y51A2D.19b  1082 YVITNPPAELRIKNTDYVYVLEQFD    1106



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