Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/Y66D12A.23
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Query: Y66D12A.23 CE28801 status:Partially_confirmed TR:Q95PZ8 protein_id:CAC70140.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
tRNA-synt_2 tRNA synthetases class II (D, K and N) 200.5 2.6e-56 1
tRNA_anti OB-fold nucleic acid binding domain 20.3 0.00033 1
IL12 Interleukin-12 alpha subunit 4.2 1.7 1
HNF-1A_C Hepatocyte nuclear factor 1 (HNF-1), alph 3.1 8.7 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
tRNA_anti 1/1 13 86 .. 1 89 [] 20.3 0.00033
HNF-1A_C 1/1 160 175 .. 1 16 [. 3.1 8.7
IL12 1/1 243 253 .. 216 226 .] 4.2 1.7
tRNA-synt_2 1/1 98 397 .. 1 363 [. 200.5 2.6e-56
Alignments of top-scoring domains:
tRNA_anti: domain 1 of 1, from 13 to 86: score 20.3, E = 0.00033
*->VtvaGrVhsvrdlgtfknadggggkliFltLrDgtg.Griqvvvfnd
t+ G+ +sv+++ gk++F+ ++ g ++ iq+v+++
Y66D12A.23 13 KTLDGWAKSVQKS----------GKNVFVKIDKGRAgEPIQLVANK- 48
evpeleklak.lkeGdvVgVtGkvkkrpeatGelellveeievl<-*
++ ++++G+ +++tG + +++a +e e ++e+++v+
Y66D12A.23 49 ------EIGQeIRVGSAIRATGSLEHSRGAQQEMEFVAEQLKVV 86
HNF-1A_C: domain 1 of 1, from 160 to 175: score 3.1, E = 8.7
*->vlTsDpeahtDqgihe<-*
v+T+ +++ +D g++e
Y66D12A.23 160 VVTTTSTEAGDGGLKE 175
IL12: domain 1 of 1, from 243 to 253: score 4.2, E = 1.7
*->InRvMSYLnSS<-*
I + SYLnSS
Y66D12A.23 243 IQHMISYLNSS 253
tRNA-synt_2: domain 1 of 1, from 98 to 397: score 200.5, E = 2.6e-56
*->dqetRyrqRyldLrmneesravfrvRskiiaaiRrfFdekGFlEVeT
+++ ++ + +l+ r n + +a +r Rs+i ++ ++fF ++ F+ ++T
Y66D12A.23 98 SPDNLRKKTHLRAR-NSKFAALLRARSAIFRETHEFFMSRDFIHIDT 143
PmlseavstdieGGGEmFRV.TLDLEnLprvsagatpFitsyfgLdkelY
P+l + +d+eGGGE+F V T + +t+ + + ++++
Y66D12A.23 144 PKL---TRNDCEGGGEVFDVvT----------TTSTE-AGDGGLKEEPMF 179
LriSpeLylkrLivgGlerVyeIgrvFRnEkgnthrHnpEFTmlEfYmAf
L +S++L+l+ + l rVy +g++FR+E +h H++EF mlE+++Af
Y66D12A.23 180 LSVSSQLHLEAMVSR-LQRVYILGPSFRAERQQSHAHLSEFHMLEAEVAF 228
adhyhDLmeltEeLlkqivkellgstqvkYdPDkqgeeldfvkpfkrism
++ +++ l+E +++++ +l+ +++++
Y66D12A.23 229 VETIDEMCTLVESYIQHMISYLN-------S--------------SKLEP 257
vdalekykgvd.p.inefflrltyedAieilkehgiEieepkefdlGtll
a+ +g + p n +f+r+ y++A+ +l +g ++ + ++++ +
Y66D12A.23 258 ETAI---IGSKiPiSNIKFPRIRYDEAVHLLALKGSKVTAK--SGFSKKN 302
qelfeefveetlikdtdPtFvydfPleisPlamrsdaedprvterfdlfi
+ +v+ + d P+Fv+++P+ ++P++m +d ++t +fdl++
Y66D12A.23 303 EL---DLVKLH---DDHPIFVTHYPVGQKPFYMARD---GQLTLSFDLLV 343
pGrGEIanGfqeLnDpddqreRFeeQarakaaGddeadeidedfvdaLeY
pG+GE+a+G+ ++ ++++++R ++++++ ++
Y66D12A.23 344 PGIGELAGGSLREQSAEELQRRGC-------------G--IDWYLEMRRR 378
GmPPhaGlGlGiDRliMll<-*
G PP++G+G+G++R+ +l
Y66D12A.23 379 GQPPTGGFGIGFERMLQYL 397