Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/Y66H1B.3
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Query: Y66H1B.3 CE20347 status:Partially_confirmed TR:Q9TYW4 protein_id:AAC69000.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Filamin Filamin/ABP280 repeat 273.2 8.8e-82 6
CH Calponin homology (CH) domain 181.8 1.1e-50 2
Big_1 Bacterial Ig-like domain (group 1) 9.8 0.087 2
Coq4 Coenzyme Q (ubiquinone) biosynthesis protein 5.0 1.8 1
NAGLU Alpha-N-acetylglucosaminidase (NAGLU) 3.5 1.8 1
B1 Protein L b1 domain 3.0 5.9 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CH 1/2 27 132 .. 1 106 [] 96.8 2.3e-25
CH 2/2 151 253 .. 1 106 [] 84.2 7.1e-22
Filamin 1/6 382 439 .. 43 100 .] 11.5 0.036
NAGLU 1/1 445 466 .. 409 430 .. 3.5 1.8
Big_1 1/2 597 629 .. 73 107 .] 1.6 32
Filamin 2/6 543 629 .. 1 100 [] 77.1 4e-22
Filamin 3/6 711 729 .. 82 100 .] 5.1 3.2
B1 1/1 787 817 .. 44 71 .] 3.0 5.9
Filamin 4/6 735 823 .. 1 100 [] 81.9 1.3e-23
Big_1 2/2 790 826 .. 70 107 .] 8.2 0.27
Filamin 5/6 829 915 .. 1 100 [] 45.1 2.2e-12
Filamin 6/6 962 1043 .. 7 100 .] 80.8 3e-23
Coq4 1/1 1034 1049 .. 1 16 [. 5.0 1.8
Alignments of top-scoring domains:
CH: domain 1 of 2, from 27 to 132: score 96.8, E = 2.3e-25
*->sqekellrWinsvlagypgkkstlPippvpvtnfftdwlkDGlaLca
+q+++++rW++++l++++ +++++ td++ DGl L+a
Y66H1B.3 27 IQQNTFTRWVKNHLQKAG----------ETIESLETDFS-DGLKLIA 62
Llnklr..................eNlnlaldaaekeGlgivlvlldpeD
L+ +l++++ ++ +++ ++++ eN++lal+++++e ++ + ++d+ +
Y66H1B.3 63 LAQVLShknvgkfnkkvafrsqklENVSLALNFFQNEENIK-IINIDSTH 111
iveaegnpdPDeklvltylwqLirrfq<-*
iv+ +n+ kl+l+++w+Li++++
Y66H1B.3 112 IVD--HNK----KLILGLVWTLILHYS 132
CH: domain 2 of 2, from 151 to 253: score 84.2, E = 7.1e-22
*->sqekellrWinsvlagypgkkstlPippvpvtnfftdwlkDGlaLca
++++ ll+Wi++ l g p ++nf++dw+ DG+aL a
Y66H1B.3 151 TPKQKLLNWIRNRLPGMP------------ISNFTSDWN-DGVALGA 184
Llnklr................eNlnlaldaaekeGlgivlvlldpeDiv
L+n+ +++ ++ ++ ++++ eN ++a+++a++ l + ++l+ p +++
Y66H1B.3 185 LVNSMApgaledwenwspndalENTEKAMKSAQDL-LKV-APLIAPAEMI 232
eaegnpdPDeklvltylwqLirrfq<-*
+++ De +v+tyl+q+ +
Y66H1B.3 233 ---HPE-IDEMSVMTYLSQFPATKP 253
Filamin: domain 1 of 6, from 382 to 439: score 11.5, E = 0.036
*->gGgltvtVegPsGaAvvevkvtDngD.GTytVsYvPtepGdYtvnVk
+G++++ V++P G+ ++ + + D+ +G ++ +Y ++ G ++vnV
Y66H1B.3 382 EGPVEAIVVDPTGK-EHRMVILDGTSpGEHSFEYKIPCIGLHSVNVF 427
ygGqhiPgSPfk<-*
+ gSPf+
Y66H1B.3 428 HKKLPLTGSPFP 439
NAGLU: domain 1 of 1, from 445 to 466: score 3.5, E = 1.8
*->pNStklVGtGMcPEGIeqNpVV<-*
+NS k G G++PEGI N VV
Y66H1B.3 445 KNSFKVWGRGIAPEGIRKNDVV 466
Big_1: domain 1 of 2, from 597 to 629: score 1.6, E = 32
*->nGvAtvtLTstkaGtytVtAslenggatsvdaktV<-*
+G A ++T+t aG+y V + l+ +g+ +d+++V
Y66H1B.3 597 DGSAILSYTPTVAGVYKVGV-LA-DGKHIQDSPFV 629
Filamin: domain 2 of 6, from 543 to 629: score 77.1, E = 4e-22
*->agDasKVkayGPGLeggSGvkvgkpaeFtVdtVddGepkaAGgGglt
+ sK++a G GLegg v++p+ F V+ ++ +l+
Y66H1B.3 543 PESSSKIRAFGAGLEGG---IVNEPCVFDVEM-------NGESKDLS 579
vtVegPsGaAvvevkvtDngDGTytVsYvPtepGdYtvnVkygGqhiPgS
+VegPs+a e+ ++++ DG+ sY+Pt++G+Y v V+ +G hi +S
Y66H1B.3 580 FAVEGPSKA---EIGCQERPDGSAILSYTPTVAGVYKVGVLADGKHIQDS 626
Pfk<-*
Pf
Y66H1B.3 627 PFV 629
Filamin: domain 3 of 6, from 711 to 729: score 5.1, E = 3.2
*->dYtvnVkygGqhiPgSPfk<-*
++ ++V +G+ +Pg Pf+
Y66H1B.3 711 KHKIDVSVAGVSVPGAPFS 729
B1: domain 1 of 1, from 787 to 817: score 3.0, E = 5.9
*->DlLkKenGkYtaDleD...gGYtinirFAGK<-*
D+L ++G +t+ +++g Y +n+ FAG
Y66H1B.3 787 DVLDNQDGSFTVKYTAqrpGAYQLNVVFAGE 817
Filamin: domain 4 of 6, from 735 to 823: score 81.9, E = 1.3e-23
*->agDasKVkayGPGLeggSGvkvgkpaeFtVdtVddGepkaAGgGglt
++DasK k+ GPG+ g v+ ++p+ Ft+d+ +AG G ++
Y66H1B.3 735 PTDASKLKIFGPGVDGP--VYSKEPTRFTIDA------TQAGPGAVE 773
vtVegPsGaAvvevkvtDngDGTytVsYvPtepGdYtvnVkygGqhiPgS
v+ + G v+ +v Dn DG++tV+Y+++ pG Y nV ++G++i S
Y66H1B.3 774 VALRDDQGE-NVDLDVLDNQDGSFTVKYTAQRPGAYQLNVVFAGEEI--S 820
Pfk<-*
P++
Y66H1B.3 821 PIE 823
Big_1: domain 2 of 2, from 790 to 826: score 8.2, E = 0.27
*->TDanGvAtvtLTstkaGtytVtAslenggatsvdaktV<-*
++++G +tv++T ++G y+ + ++ g s ++ +V
Y66H1B.3 790 DNQDGSFTVKYTAQRPGAYQLNVVFA-GEEISPIEINV 826
[output cut off at A = 10 top alignments]