Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/Y77E11A.1
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Query: Y77E11A.1 CE25610 status:Partially_confirmed TR:Q9N4A5 protein_id:AAF36071.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
hexokinase Hexokinase 194.6 1.4e-54 1
hexokinase2 Hexokinase 171.7 1.2e-47 1
UDPG_MGDP_dh UDP-glucose/GDP-mannose dehydrogenase fa 11.0 0.23 1
GIDA Glucose inhibited division protein A 2.1 9.3 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
hexokinase 1/1 2 195 .. 1 224 [. 194.6 1.4e-54
UDPG_MGDP_dh 1/1 163 196 .. 65 99 .] 11.0 0.23
GIDA 1/1 376 392 .. 611 629 .] 2.1 9.3
hexokinase2 1/1 207 448 .. 1 259 [] 171.7 1.2e-47
Alignments of top-scoring domains:
hexokinase: domain 1 of 1, from 2 to 195: score 194.6, E = 1.4e-54
*->aelsqavdellaqFrvstEtLrevvkrFikemeKGLsahkeggnlAs
+ l +v+e+la Fr+++E+L+e+ +m++GL+ k+ g+
Y77E11A.1 2 KVLPPEVEEILAKFRLNREQLQEISEKVEQQMKMGLA--KTQGS--- 43
PHeksvkMlPtfVrstPdGtEkGdFLALDLGGTNfRVllVklggngegWk
s++MlP++V ++PdGtE+G ++A+DL G N+R++l + +g g +
Y77E11A.1 44 ----SIAMLPSYVPALPDGTETGKYVAIDLSGKNLRIMLLTMNGAG---T 86
vemtqsk.YrlPFtGYHeelmtgtgvTaeqLFDfiAeCikdFmdeqgpdd
++ ++Y ++m gtg +qLF fi+ C++ F++e+g+
Y77E11A.1 87 TPTHETVnYIVA-----NHVMKGTG---DQLFTFIVNCLQRFLQEFGL-- 126
lakGkkekLpLGFTFSFPcsQtsInegiLirWTKGFkiGRAtnsgvEGhD
++ +Lp+GF FS+Pc sI ++ L+ WTKGF+i ++ +D
Y77E11A.1 127 ----VDANLPIGFVFSYPCELLSIRSARLLWWTKGFDI-----KDCLQRD 167
VVpLLreAIkrrgipdidVVAvvNDTVG<-*
V LL eA++ + + Av NDTVG
Y77E11A.1 168 IVALLEEALEMNMSTKVSIKAVMNDTVG 195
UDPG_MGDP_dh: domain 1 of 1, from 163 to 196: score 11.0, E = 0.23
*->CfpkDpraLtakAeelGlpaklilleavvnvNmpq<-*
C+++D++aL + A e ++ +k ++av+n+ q
Y77E11A.1 163 CLQRDIVALLEEALEMNMSTK-VSIKAVMNDTVGQ 196
GIDA: domain 1 of 1, from 376 to 392: score 2.1, E = 9.3
*->ItPaaIsvLyrlvhLkkqe<-*
I +aaIs+L l+hL+ +
Y77E11A.1 376 IVAAAISAL--LRHLELSS 392
hexokinase2: domain 1 of 1, from 207 to 448: score 171.7, E = 1.2e-47
*->eceiGlIvGTGtNaCYmEemrnIekleGkLkdDipKedegrMcINmE
ec iG+++G G+N Y E+ + I+k + + d ++M++ +E
Y77E11A.1 207 ECTIGVVIGYGCNSSYLEKTSRITKFDA----KARGYDHDNMIVVTE 249
WGaFGDnghldlprTkYDvviDeeSpNPGqQlFEKMISGmYLGEivRliL
W FG g+ld+++T +D+++D S G+Ql K+ + +Y GE+vR++L
Y77E11A.1 250 WEEFGKHGELDDILTQFDREVDAASVHKGKQLIDKLCGALYIGEVVRRVL 299
ldLakeGlLFkGqdspkLktpgsfeTsvlSrIEsDpsenledvraiLqta
L+ +LF+Gq +kL++ sf T+++S+I+ + ++ r i ++
Y77E11A.1 300 SQLVLDRVLFEGQSCEKLDEDESFPTKYISEILGEEEGVFKACRRICEE- 348
Lglet.TdeerklvrrvCeaVstRAArLcaaglAAilkkirenrgrerlk
L +e +++ + +++r+vC ++s+R A+ +aa++ A+l+ +e ++
Y77E11A.1 349 LEVEMhGTGDYIIIREVCDVISRRGASIVAAAISALLRH------LELSS 392
vtvGvDGSVYkkyPgFkerlRhaeaLrdLlpetekecdkpvsiipAEDGS
v +Gv+G + +P + +l e L +L+p + ++pA++GS
Y77E11A.1 393 VKIGVGGALIQFHPTYHQML--KEKLEELTPI---TMK--FELVPADEGS 435
GkGAAlvaAVaak<-*
GAAl+aAVa++
Y77E11A.1 436 CQGAALIAAVAER 448