Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/ZC101.2b
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Query: ZC101.2b CE15030 locus:unc-52 UNC-52 membrane proteoglycan status:Partially_confirmed TR:O18261 protein_id:CAB07704.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
laminin_B Laminin B (Domain IV) 512.6 2.8e-150 2
laminin_EGF Laminin EGF-like (Domains III and V) 221.6 1.1e-62 7
ldl_recept_a Low-density lipoprotein receptor domain 182.1 5.7e-54 3
ig Immunoglobulin domain 60.2 5.1e-15 2
RTX RTX N-terminal domain 5.5 0.18 1
fn2 Fibronectin type II domain 4.8 1.6 1
DSL Delta serrate ligand 4.5 5.2 1
filament_head Intermediate filament head (DNA binding 4.3 4.7 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
ig 1/2 59 116 .. 1 50 [] 38.4 5.8e-09
ldl_recept_a 1/3 147 185 .. 1 43 [] 61.2 4.5e-17
ldl_recept_a 2/3 188 226 .. 1 43 [] 69.1 1.7e-19
ldl_recept_a 3/3 231 270 .. 1 43 [] 67.7 4.6e-19
ig 2/2 286 346 .. 1 50 [] 24.0 5.6e-05
laminin_EGF 1/7 374 429 .. 4 59 .] 28.8 9.6e-07
RTX 1/1 483 491 .. 659 667 .] 5.5 0.18
laminin_B 1/2 498 632 .. 1 148 [] 259.6 4.2e-74
laminin_EGF 2/7 633 652 .. 27 47 .. 16.1 0.0042
laminin_EGF 3/7 686 718 .. 25 59 .] 41.9 1.7e-10
filament_head 1/1 730 738 .. 1 9 [. 4.3 4.7
laminin_B 2/2 790 920 .. 1 148 [] 254.2 1.8e-72
laminin_EGF 4/7 921 940 .. 27 47 .. 20.4 0.00025
fn2 1/1 965 971 .. 36 42 .] 4.8 1.6
laminin_EGF 5/7 955 1002 .. 1 59 [] 70.5 1.1e-18
laminin_EGF 6/7 1011 1058 .. 1 59 [] 59.2 1.9e-15
DSL 1/1 1080 1091 .. 56 67 .] 4.5 5.2
laminin_EGF 7/7 1061 1109 .. 1 59 [] 34.4 2.4e-08
Alignments of top-scoring domains:
ig: domain 1 of 2, from 59 to 116: score 38.4, E = 5.8e-09
*->GesvtLtCsvs.gfgpp.p.vtWlrngk.le....tsslslti.svt
G +v++ C+++++ ++ p+v+W r g++l+++ + s+ +lti++v+
ZC101.2b 59 GRDVSFECRARtSDNSVyPtVRWARVGGpLPssahDSGGRLTInPVQ 105
peDsgGtYtCvv<-*
+D+ GtY Cv
ZC101.2b 106 LSDA-GTYICVS 116
ldl_recept_a: domain 1 of 3, from 147 to 185: score 61.2, E = 4.5e-17
*->stCggpdeFqCgsgrrCIprswvCDGdpDCeDGSDEslenCaa<-*
++C+ +de Cg+++ C+++++vCDG+pDC+D SDE +nC+a
ZC101.2b 147 GQCM-ADEKACGNNE-CVKNDYVCDGEPDCRDRSDE--ANCPA 185
ldl_recept_a: domain 2 of 3, from 188 to 226: score 69.1, E = 1.7e-19
*->stCggpdeFqCgsgrrCIprswvCDGdpDCeDGSDEslenCaa<-*
+tC+ p+eF+C++++ C+ + w+CDGd+DC+D SDE nC a
ZC101.2b 188 RTCE-PNEFKCNNNK-CVQKMWLCDGDDDCGDNSDE--LNCNA 226
ldl_recept_a: domain 3 of 3, from 231 to 270: score 67.7, E = 4.6e-19
*->stCggpdeFqCgsgrrCIprswvCDGdpDCeDGSDEslenCaa<-*
s+C+ p eFqC+++r+C+p+s++CDG +DC+DGSDE ++C++
ZC101.2b 231 SDCK-PTEFQCHDRRQCVPSSFHCDGTNDCHDGSDE--VGCVQ 270
ig: domain 2 of 2, from 286 to 346: score 24.0, E = 5.6e-05
*->GesvtLtCsvsgfgpp.p.vtWlrngk.le..........tsslslt
G + +LtC + + p+p ++W+ n +++ ++++ ++++ + +lt
ZC101.2b 286 GTTFSLTCKAV--AVPePyINWRLNWGpVCepprclqtseGGYGTLT 330
i.svtpeDsgGtYtCvv<-*
i++++p D G YtC++
ZC101.2b 331 IhDAQPVDQ-GAYTCEA 346
laminin_EGF: domain 1 of 7, from 374 to 429: score 28.8, E = 9.6e-07
*->nphGslsddtCdsddelf..geetGqClkCkpnvtGrrCdrCkpGyy
+p + +++++Cd ++ + ++ G C Ck vtG++Cd+CkpG +
ZC101.2b 374 PPTAPPQRASCDTRGAVTpyPNNYGTCE-CKSQVTGPNCDQCKPGAF 419
glpsgdpgqgC<-*
l++++p+ gC
ZC101.2b 420 HLSEKSPE-GC 429
RTX: domain 1 of 1, from 483 to 491: score 5.5, E = 0.18
*->tGaLTIDgt<-*
tG+LT+Dgt
ZC101.2b 483 TGYLTFDGT 491
laminin_B: domain 1 of 2, from 498 to 632: score 259.6, E = 4.2e-74
*->YWrlPekFLGDkvtsYGGkLkYsvafdgPvegvgstsnseadViLkG
YWrlP++FLGDkvt+YGGk++++++f+g +g +++se++V+LkG
ZC101.2b 498 YWRLPQRFLGDKVTAYGGKMEFEIEFSG----SG-HHSSEPMVVLKG 539
nglrlsvplraqgnslrPseervkvtvrlhEtfwkdfnsqpaKavtredl
n+++l++ +r+q+++lr s+++v++tv+++Et+ ++++++a a+tredl
ZC101.2b 540 NQNILVHRVRNQEHVLR-SDSPVRITVETYETN--YEQLNGA-AATREDL 585
lsvLanLtaiLIRATYNsakqaqsrLddVsLeiArpgaqgpaEdvvAaeV
l+vLa+L+a+LIRAT+ +a+q++++L+dVs+eiA+++++ p d++A+eV
ZC101.2b 586 LMVLADLDAFLIRATH-VAHQTSTSLGDVSWEIAVDRYT-P--DGLALEV 631
E<-*
E
ZC101.2b 632 E 632
laminin_EGF: domain 2 of 7, from 633 to 652: score 16.1, E = 0.0042
*->qClkCkpnvtGrrCdrCkpGy<-*
qC+ C p++ G+ C+ C+pGy
ZC101.2b 633 QCV-CPPGYLGTSCEDCAPGY 652
laminin_EGF: domain 3 of 7, from 686 to 718: score 41.9, E = 1.7e-10
*->tGqClkCkpnvtGrrCdrCkpGyyglpsgdpgqgC<-*
+GqC+ Ck v G++CdrC+p+ +gl+ +++qgC
ZC101.2b 686 QGQCQ-CKASVIGPNCDRCAPNSFGLAP-TNPQGC 718
[output cut off at A = 10 top alignments]