Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/ZC196.7
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: ZC196.7 CE15078 locus:glr-5 ligand-gated ionic channel protein status:Partially_confirmed TR:O01623 protein_id:AAB52291.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
lig_chan Ligand-gated ion channel 459.7 2.5e-134 1
SBP_bac_3 Bacterial extracellular solute-bindin 20.4 2.8e-05 1
ANF_receptor Receptor family ligand binding region 7.7 0.42 1
PKD PKD domain 6.3 0.87 1
Glyco_tran_WecB Glycosyl transferase WecB/TagA/CpsF f 4.7 5 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
ANF_receptor 1/1 139 174 .. 141 180 .. 7.7 0.42
PKD 1/1 408 435 .. 1 32 [. 6.3 0.87
SBP_bac_3 1/1 460 548 .. 16 95 .. 20.4 2.8e-05
lig_chan 1/1 566 865 .. 1 316 [] 459.7 2.5e-134
Glyco_tran_WecB 1/1 840 871 .. 1 34 [. 4.7 5
Alignments of top-scoring domains:
ANF_receptor: domain 1 of 1, from 139 to 174: score 7.7, E = 0.42
*->ealvdllkhfgWtwvalvysdddygeegvaaliealeerg<-*
ea+vd++ h++W++++lvy+ d+ +++l++ le+++
ZC196.7 139 EAVVDMFTHWRWNRIVLVYEGDE----RIRRLEQLLESEE 174
PKD: domain 1 of 1, from 408 to 435: score 6.3, E = 0.87
*->epvpglsvsasaveegpsvvalgetVtFtass<-*
ep+++++v+ s g+s++ l+++V++++ +
ZC196.7 408 EPATNVHVNMS----GDSKAQLQRNVQVSDEL 435
SBP_bac_3: domain 1 of 1, from 460 to 548: score 20.4, E = 2.8e-05
*->deddsGkltGfDvDlakaiAkrlg.............gvkvefvptd
d++ k+ Gf +Dl+ ++ k+lg + + + ++++ g ++ + +
ZC196.7 460 DAN--SKFEGFCIDLLAELSKDLGftytihavkdgkyG-NDKYGNGS 503
wdglipaLqsGkvDiiiagmtiTpeRkkkvdFfSdPYytsgqvllv<-*
wdg++ G++ +++a +t++ +R + vdF + P+++ g+ +l+
ZC196.7 504 WDGMMGEILRGEAEMAVAPLTVNYRRSEAVDF-TKPFLSLGISILY 548
lig_chan: domain 1 of 1, from 566 to 865: score 459.7, E = 2.5e-134
*->slevWlcilaayllvsvvlfllerwfsPyewrnnlqpypciedd...
s+++W+ i+ +++ v++ ++++++ Pyew+ n+++++++e+++
ZC196.7 566 SWQIWTAIATSIITVTLGMYFVAN-VTPYEWNLNFSCCTAHEPHpaa 611
....eaPqrspeeeenqftlsnslWFsfgalmqQGcdelPrslSgRivvg
++ q++p +++n+++++n++W+++++++ +Gcd+ Pr++S+R+++g
ZC196.7 612 afatN--QEAPIVMSNNYSFWNTVWYVLSTMLKGGCDFGPRAVSTRLLGG 659
vWwfFaLilisSYTANLAAFLTvermqspIesleDLakqtpkieYGtlrg
+Ww+F L++is YTANLAA+LTv+r++ pI++l+DLa+qt +i+YGt+rg
ZC196.7 660 TWWVFYLVIISAYTANLAAVLTVSRPYIPIKNLDDLANQT-TISYGTIRG 708
gstfaffkesniptyrrmweymksnkgrskWYpvdampsvfvksyeeGvq
gst++ff+es i+ + +mw ymk+++ vfv s+ Gv+
ZC196.7 709 GSTMQFFQESRIAAHVKMWQYMKDKD-------------VFVTSNGKGVE 745
rVrkgeenglyAFlmEstyleyevarnpdCdLttvGevlfdtkGYGIAlp
r++++ n yA+lmEst+leye+++n C+Lt++G+ ++++kGYGIAl
ZC196.7 746 RALSM--N--YAYLMESTSLEYETQQN--CNLTQIGG-VLGSKGYGIALA 788
kgSPlrdklSlAILeLsEsGeLekLknKWwkkkgqgnCsdessa..gsss
k S ++d +S++IL + +G +e+ k+KWw++kg +C ++ sa +++
ZC196.7 789 KKSEWTDRISRQILLYAKRGIIEMKKTKWWRSKGA-ACASTASAvkHDRF 837
aLglenfaGlFlvLgiGlvlallvalfE<-*
aL+++n+aGlF++Lg+G+vla++v +fE
ZC196.7 838 ALSMYNVAGLFITLGVGIVLAAIVVIFE 865
Glyco_tran_WecB: domain 1 of 1, from 840 to 871: score 4.7, E = 5
*->elvneAdLilpDGiGvVlaarllggglplpeRva<-*
++n A L ++ G+G+Vlaa ++ + +l +R++
ZC196.7 840 SMYNVAGLFITLGVGIVLAAIVVI-F-ELIHRCH 871