Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm5/seq/ZK1010.9
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Query:  ZK1010.9  CE23490  locus:snf-7 Sodium:neurotransmitter symporter status:Partially_confirmed TR:O18288 protein_id:CAB04115.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
SNF      Sodium:neurotransmitter symporter family       352.0   6.4e-102   2

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
SNF        1/2      66   175 ..     1   119 [.    91.6  1.3e-24
SNF        2/2     191   587 ..   188   609 .]   266.9  2.7e-76

Alignments of top-scoring domains:
SNF: domain 1 of 2, from 66 to 175: score 91.6, E = 1.3e-24
                   *->RetWsgKldFvLSvvGfaVGLGNVWRFPYLCYKNGGGAFLiPYlIfL
                      R+++ g ++  LS+ G aVGLGN+WRFP ++YKNGG  FLi Y++
    ZK1010.9    66    RQAFRG-IESFLSSLGQAVGLGNIWRFPTTAYKNGGLSFLIAYVVCG 111

                   ivaGIPLFFLElaLGQytreGsitvWrkKiLDKGKGIcPlFkGiGYasiv
                   i   +P + +E aLGQy  + ++ ++r+          P+++G+G++ ++
    ZK1010.9   112 ILFAVPAIHMEFALGQYAAKSPPAAFRR--------MMPILEGVGWMTCL 153

                   iafyigiYYnVIiAWalyYLfs<-*
                   +  +ig+YY+++i+W + YLf+
    ZK1010.9   154 VGAIIGVYYMIVISWIVLYLFN    175

SNF: domain 2 of 2, from 191 to 587: score 266.9, E = 2.7e-76
                   *->SsGIsdlGelrWeLtlCLllaWivvYfclwKGVksGsGKVVYFTATF
                      S+G +d+ +++ ++++   ++W+++ ++l++G k  +GK +Y+T ++
    ZK1010.9   191    STGFTDFNSINVPMLAAVAVCWVIAIISLIRGMKA-IGKLSYYTVLL 236

                   PYvvLivLLiRGVTLPGAadGIkfYL........tPdfskLldPqVWiDA
                   PY + i L iRG+TL+GA++G+ f++ +++++ ++ df  L dP VWi+A
    ZK1010.9   237 PYAIIIALMIRGLTLEGASTGLHFLFwgkpneygHYDFAGLYDPDVWIAA 286

                   atQIFFSLGiGFGvLiAlaSYNkfhNNcYrDaiivsfiNsiTSflAGFvI
                   + Q +FSL+iG+G+L+  +SYNk+ +N YrDa +v +  +  S+l G ++
    ZK1010.9   287 LMQMCFSLSIGQGGLMNIGSYNKKTYNWYRDAYLVVLCDTLMSLLGGTAV 336

                   FSiLGFMANIvqeqGvpHvNlSalTaDYsvYdvIs......eVAeseFvL
                   FS LGF A   + +++                 Is++++ +eV ++
    ZK1010.9   337 FSTLGFLA---EQRNIS----------------ISnpkgfnEVVQE---- 363

                   gLaClEDELdKVqGPGLAFiaYPeAvtmlPlSpfWavLFFlMLltLGLDS
                                G  LAFi+Y+eA++++P++ +W  LFF+ML +LG+ +
    ZK1010.9   364 -------------GHALAFIVYTEAIAQMPYPFLWYALFFVMLFLLGIST 400

                   qFggvEgiITAlvDefprvlilkkrrelftlgvcvasfligLlmvTeGGi
                    ++++E++ + l+D f   ++l+++r ++++ v+ + fl+gL+m++++G
    ZK1010.9   401 EIVIIETVCSCLADRF---HYLRQHRWITVVTVSTTFFLLGLVMTSDAGF 447

                   YvftLFDdYaAsGfsLLfvvflEciavawvYGidrFyddIkeM.......
                   Y+f+L D+Y+A+ +s  + ++++c+ v w YG+d+F  dI eM ++++++
    ZK1010.9   448 YWFDLYDEYSAG-VSATIGTAIMCLTVCWCYGLDNFRADIREMweepesr 496

                   ..lGFrPgly.wklCWkfvsPlillfififsl..vqyGlkPltYnnvIKE
                    +++  Pg y w + W+fv+P+++l+i  + + +++y   P + +++
    ZK1010.9   497 ldKYLGPGAYvWTIVWRFVTPICCLVIMFAWIwdKKY---PFKGDSK--- 540

                   AEyYvYPnWavalGWlmALSSmlciPlymiykllstkGdslkerlqqltt
                        YP+ + a+GW+ A++   ++P+++ ++ ++ k++++  r   +++
    ZK1010.9   541 ----KYPPVFDAFGWFVAALPFFVVPVFAGFAIKRFKDLNIPIRGVFMVQ 586

                   P<-*
                   +
    ZK1010.9   587 K    587



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