Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm5/seq/ZK354.2a
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Query:  ZK354.2a  CE15314   protein kinase status:Partially_confirmed TR:P91571 protein_id:AAB42257.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
pkinase  Protein kinase domain                           65.1    6.1e-17   2
GST_C    Glutathione S-transferase, C-terminal domain     3.7        9.7   1
MT-A70   MT-A70                                           2.9        6.9   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
pkinase    1/2      21    51 ..     1    32 [.    25.0  7.3e-06
MT-A70     1/1     143   155 ..   181   195 .]     2.9      6.9
pkinase    2/2      89   172 ..    71   149 ..    38.8  1.2e-09
GST_C      1/1     281   373 ..     1    58 [.     3.7      9.7

Alignments of top-scoring domains:
pkinase: domain 1 of 2, from 21 to 51: score 25.0, E = 7.3e-06
                   *->yelleklGeGsfGkVykakhkdktgkiVAvKi<-*
                      ye+ ++l  G+fG++ykak+  ++gk +AvK+
    ZK354.2a    21    YEVTKPLATGTFGSIYKAKRE-SDGKFFAVKC    51

MT-A70: domain 1 of 1, from 143 to 155: score 2.9, E = 6.9
                   *->RdhnlrPgWltwGne<-*
                      Rd  + P+ +++G+e
    ZK354.2a   143    RD--IKPSHFCIGRE    155

pkinase: domain 2 of 2, from 89 to 172: score 38.8, E = 1.2e-09
                   *->ddhlylvmEymegGdLfdylrrng..gplsekeakkialQilrGleY
                      ++ l +vm++ +   Lfd++++ ++++++s+   +++a Q+l ++
    ZK354.2a    89    NRFLFIVMPLYGE-NLFDLMMNTNkdRKFSMATGLHLAEQTLTAIRD 134

                   LHsngivHRDLKpeNILlden....dgtvKiaDFGLAr<-*
                   LH+ng++HRD+Kp+ + + ++ ++++++v + DFGL++
    ZK354.2a   135 LHRNGFIHRDIKPSHFCIGREvdgqHHQVYLLDFGLCK    172

GST_C: domain 1 of 1, from 281 to 373: score 3.7, E = 9.7
                   *->Gkdpderaaaerarwdmiedsrfadlrldlawlpygkperg......
                      +kd      ae   +d+i+d +++ l+ + ++   ++p++   ++ +
    ZK354.2a   281    PKDV-----AEFVEYDRIAD-GIQKLFEKSKSNTQEPPDWDcmtdyk 321

                   ...................................aekdeeeveealekl
                   +++ ++ +   +++ + +++ + ++++++ ++++  + ++eev+++++k+
    ZK354.2a   322 gpgyqqvpmiappevglkpemdfgksdpgagggsvEQPKKEEVDKKKKKK 371

                   lk<-*
                   +k
    ZK354.2a   372 KK    373



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