Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm5a/seq/ZK520.4c
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Query:  ZK520.4c  CE16729  locus:cul-2 Cullin family (2 domains) status:Partially_confirmed TR:Q8WQ96 protein_id:CAD18893.1

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N
--------       -----------                              -----    ------- ---
Cullin         Cullin family                           1186.1          0   2
ribonuc_red_sm Ribonucleotide reductase, small chain      6.1       0.51   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
ribonuc_red_sm   1/1     446   476 ..     1    33 [.     6.1     0.51
Cullin           1/2      26   506 ..     1   550 [.   816.0 1.4e-241
Cullin           2/2     528   745 .]   605   850 .]   377.6 1.2e-109

Alignments of top-scoring domains:
ribonuc_red_sm: domain 1 of 1, from 446 to 476: score 6.1, E = 0.51
                   *->epmLfenpsrfvlYpiqhpdiwEelykkaisnf<-*
                      e++L  +++++ +  i+++di+ ++y+k ++n+
    ZK520.4c   446    EAKL--DSAIVIFRYIEDKDIFQKFYSKMLANR    476

Cullin: domain 1 of 2, from 26 to 506: score 816.0, E = 1.4e-241
                   *->vdfeetWekLkpginqilrnekdmadTnvdvrksmtklsymeLYtnV
                      v+f+++W++L+p i +i++            ++++t+ ++++++++V
    ZK520.4c    26    VEFDKVWVQLRPSIIDIIN------------LRPITNVQWHHKFSDV 60

                   YniclskslstslrgSpvrtggAdrlGekLYnrLkeyvVifaklikeyva
                   Y+ic+s++               ++l+e+LYn++k++       i+e+v+
    ZK520.4c    61 YDICVSIP---------------TPLSERLYNEVKAC-------IQEHVR 88

                   alrkrvWislsndellLetyvkeWerftvsakiinniFkYLnrvwvkker
                   ++r++  i + +++llL++y+k+W++f+++a++i+++F+YLn+++vk++r
    ZK520.4c    89 QKRQD--IVDVDPDLLLQEYHKMWRVFHEGAIFIHRLFGYLNKQFVKQKR 136

                   sTdlDlfaqYaavdgkepiyeiytLaLdiWkevlfknFikdklidalLel
                   +TdlD+faqYaa+ + ++++ei++LaL+iWke+l+k+ i ++l++ lL+
    ZK520.4c   137 CTDLDNFAQYAAFLQIPDVKEIGCLALEIWKEDLVKT-ILPQLVKLLLIA 185

                   ieleRkGniinrahlisgvveslveLgiddsDtdAke.....akkkklsv
                   i+++RkGn++++a+++sgv++s+v+++++d+D++++e+ + +a+++++++
    ZK520.4c   186 IDNDRKGNFPHIANEVSGVINSFVKMEETDFDVVPAEgarykARESTTAF 235

                   YkesFEkpFLsaTeefYkkessnyLqelnsvteYmkkaekrLeeEseera
                   Y+esFEkp+L++Te++Y+  ++++L++l s++eYm+++   Le+E e+ra
    ZK520.4c   236 YQESFEKPLLTDTEQYYSALAQKMLTDL-SCSEYMEQVIVLLEQE-EMRA 283

                   krYLhesRsntkkkLlevcenvLItshldtLhaefsggvkelidakkied
                   k+YLhes   +++k+++ c++v+I+ h+d+Lha +++    li++++++d
    ZK520.4c   284 KKYLHES---SVEKVITLCQKVMIKAHKDKLHAVCHD----LITNEENKD 326

                   LqrmYrLlrrvpnGeleelrksleeyikkeGlnaisnlaseagegkMkla
                   L++mYrLl++++ G l+ ++k++eey+kk+Gl+a+s+l+
    ZK520.4c   327 LRNMYRLLKPIQAG-LSVMVKEFEEYVKKKGLEAVSRLT----------- 364

                   llsalatdPktyVqeLLevhkkfssLvntaFnsavdDagflqaLDkAfet
                        ++ P+++V+++L+v++kf+++ + +F+   dD +f++ LDkA+++
    ZK520.4c   365 ----GENVPQQFVENVLRVYNKFNDMKTAVFM---DDGEFSSGLDKALQG 407

                   FVNsnevsklappaksssksaELLAkYcDdLLkKsklsKkadetelEdkL
                   +VNs+e+ +      s++k++E+LA+Y+D LLkKs  +K+++et+lE+kL
    ZK520.4c   408 VVNSKEPGQ------SVPKASERLARYTDGLLKKS--TKGLSETDLEAKL 449

                   devivvFkYiedKDVFekyYkkmLAKRLiletSaSdDaEemMisKLKqac
                   d++iv+F+YiedKD+F+k+Y+kmLA+RLi+ tS+S+DaEe Mi+KLKqac
    ZK520.4c   450 DSAIVIFRYIEDKDIFQKFYSKMLANRLIASTSISMDAEELMINKLKQAC 499

                   GPyefTsK<-*
                   G yefTs+
    ZK520.4c   500 G-YEFTSS    506

Cullin: domain 2 of 2, from 528 to 745: score 377.6, E = 1.2e-109
                   *->eisLPkeLedsleeFeeFYsskHnGRKLtWlhsLsrGevkanfnpgk
                      +++LP+ L+++++eFe+FY+ kHnGRKLtWl+++s+G+v+ ++++++
    ZK520.4c   528    NFHLPRILQPVIQEFEKFYTGKHNGRKLTWLFNMSQGDVRLTYLDKQ 574

                   katYvLqvttfQmaiLLlFNdrlrdsitveeiqeltdaTeipedeLkrtl
                      Yv+q++++Qma LL+F++r  d+i v++i e   +++++ d+L +t+
    ZK520.4c   575 ---YVAQMYVYQMAALLCFERR--DAILVKDIGE---EIGVSGDYLLKTI 616

                   qSLllikakvlvllkkskkedevKesereltpdtkFsvNenFssknKkvR
                   +++l+++     l++++++          lt+d+++++N+ +  ++K+++
    ZK520.4c   617 RTILDVTL----LTCDDQN----------LTADSLVRLNMSM--TSKRMK 650

                   vkinanlvqplqkeaeqEteevhetVeeDRklelqAaIVRIMKaRKkLkH
                   ++++a+  q++ k  e E+e+v +tV +DRk+++++aIVRIMK+RK+LkH
    ZK520.4c   651 FRLQAP--QVN-KAVEKEQEAVANTVSQDRKYYMECAIVRIMKTRKVLKH 697

                   nqLvtEviqQlksRFkPsvsmIKkcIEsLIEKeYleRdeddkdtYeYLA<
                   n+LvtE+++Q+k+RF+P+v++IKk+IE+LIEK+Y++R+ d++d+Y+YLA
    ZK520.4c   698 NALVTEIMDQTKGRFSPDVPFIKKSIEDLIEKMYIQRT-DQNDEYQYLA  745

                   -*

    ZK520.4c     -    -



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