Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5b/seq/ZK675.1
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Query: ZK675.1 CE01720 locus:ptc-1 membrane protein patched status:Partially_confirmed TR:Q09614 protein_id:CAA86843.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Patched Patched family 37.6 4.8e-11 2
Got1 Got1-like family 4.3 6.1 1
DUF661 Uncharacterised BCR (COG3801) 3.9 6.6 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DUF661 1/1 592 610 .. 125 143 .] 3.9 6.6
Got1 1/1 771 789 .. 78 101 .] 4.3 6.1
Patched 1/2 686 918 .. 296 550 .. 48.6 2.1e-14
Patched 2/2 1172 1338 .. 762 957 .] -6.7 1.5e+03
Alignments of top-scoring domains:
DUF661: domain 1 of 1, from 592 to 610: score 3.9, E = 6.6
*->eraWkaqAPKkllkAfaaa<-*
+ aW +A ++l+A+ +
ZK675.1 592 MDAWNETAAEQVLQAWQRN 610
Got1: domain 1 of 1, from 771 to 789: score 4.3, E = 6.1
*->ivvFLRsvPviGsilnlPfIrpiv<-*
i +FL G++l +P++r+++
ZK675.1 771 ILSFL-----TGTLLPIPALRSFC 789
Patched: domain 1 of 2, from 686 to 918: score 48.6, E = 2.1e-14
*->LAilgvltPlmAivsAfGlLfwlGfrFnsIlc.VmPFLVLGAIGVDD
LA++gvl+ A v+++Gl +w+G+ Fn+ ++++ PFL LG IGVD+
ZK675.1 686 LALAGVLVVTFASVAGLGLATWFGIEFNAATTqIVPFLTLG-IGVDN 731
mFLMvhaWqrttrslssrarKvvkkRmgevlvEaGPSItITSlTnvLSFg
mF ++h +++ + + m+ + E+G SI+ TS+ n+LSF
ZK675.1 732 MFMLLHNYRDVVKLAG------GHAEMAILMRETGMSILCTSINNILSFL 775
IGaiTptPeIqlFCiytavAiffdfiYQlTFFaAilaiagkyEmkgrhsl
G++ p+P+ + FC+ +++ + f fi lT++ Ai +i +++ ++r l
ZK675.1 776 TGTLLPIPALRSFCAQSSILLTFNFIAILTIYPAIISIDLRRKKAQRRDL 825
flriTakavdaaetespkkl.....kkqrlksrgsakaaPvekegeknSk
++ + t++++ + +++k+q +++ g a+ +
ZK675.1 826 VCC------LYGDTREESYSmiskpKIQSKRIIG-AP------------S 856
fseveesles....eksssdssksheaeqktavvkfflniYcpfllnpkv
++ + ++ ssd+++ ++++ f++ +Y pf++ p
ZK675.1 857 EASIMQQFDGitqaQMASSDDPAPWSLHS------FIRYYYIPFISKPAS 900
rvcvllvyvvYlaiaiYG<-*
+v+++++ + l++++ G
ZK675.1 901 KVAIIVGCCALLGASFIG 918
Patched: domain 2 of 2, from 1172 to 1338: score -6.7, E = 1.5e+03
*->qilsilpttiQsiiwtlicMavVCflFIpnpitvfvitvsiaSIdiG
q+l ++ +++Q i + i +++V +++ np +++ +++ + ++
ZK675.1 1172 QYLFLTGNLMQAISIITISVFCVISVLLFNPWAALMVVCILGIMTCE 1218
VfGfLSLWGVdLDPisMitiIMSIGFSVDfsAHiaYhFyrskgsesrsik
+Gf+ L G++L P+s +t I ++G V+f+ H+ F ++ g
ZK675.1 1219 LAGFMGLVGIKLNPVSAVTLITAVGIGVEFTVHVVVSFLTALG------- 1261
kiplktpdeRvadALealGWPviQAalSTiLcvlvLlFVps.YmvvvFfK
t ++R +A + Pvi+++ ST+L++l L F + + v+ Ff
ZK675.1 1262 -----TRSQRTSSAVDRVFVPVIHGSFSTLLGILMLGFSEFeFVVKYFFI 1306
TifLVVvlGlLHGLifLPilLslfvtssrifggdviirtsnakikkpseq
++ + +G++ GLi+LP+lLs f + ++ +++
ZK675.1 1307 VMTALICIGIINGLILLPVLLSWFGP------------------RREISP 1338
<-*
ZK675.1 - -