Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5c/seq/ZK945.9
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Query: ZK945.9 CE25697 locus:lov-1 polycistic kidney disease protein 1 like with repeated domains at the N-terminus status:Partially_confirme
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
PLAT PLAT/LH2 domain 92.5 2.5e-26 1
GPS Latrophilin/CL-1-like GPS domain 60.1 3.5e-15 1
ion_trans Ion transport protein 13.4 0.02 2
COX2 Cytochrome C oxidase subunit II, periplasmi 5.0 3.3 1
ApoC-I Apolipoprotein C-I (ApoC-1) 4.2 5.6 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
ApoC-I 1/1 366 378 .. 1 13 [. 4.2 5.6
ion_trans 1/2 248 1352 .. 113 129 .. -51.4 5.9e+04
COX2 1/1 1632 1651 .. 118 137 .] 5.0 3.3
GPS 1/1 2071 2120 .. 1 54 [] 60.1 3.5e-15
PLAT 1/1 2182 2307 .. 1 129 [] 92.5 2.5e-26
ion_trans 2/2 2894 3062 .. 1 228 [] 32.8 1e-07
Alignments of top-scoring domains:
ApoC-I: domain 1 of 1, from 366 to 378: score 4.2, E = 5.6
*->apdlsstlesiPD<-*
+p++ stl s+PD
ZK945.9 366 TPEITSTLSSLPD 378
ion_trans: domain 1 of 2, from 248 to 1352: score -51.4, E = 5.9e+04
*->e..............................................
+++++++ ++ +++ ++++ + + ++++++++++++++ +++ ++++
ZK945.9 248 Rtsgsptlrrmkrdagdntcdytiestststttpttttvtstvtstt 294
..................................................
+ ++++++ ++ ++++++++++++ ++++++ +++ +++++++++++++
ZK945.9 295 tvptststvttamstststpststtieststtftstaststsststtqqs 344
..................................................
+++ ++++++++ +++ +++++++ +++ ++ +++ + ++++++++
ZK945.9 345 sstitsspssttlstsipttttpeitstlsslpdnaicsyldetttsttf 394
..................................................
+++ ++++++++++++++++ ++++++ ++++++++ ++++ +++++++
ZK945.9 395 tttmltsttteepststtttevtstsstvttteptttlttstaststtep 444
..................................................
++++ ++++++++ +++ +++++++++ ++++++++++++++++ +++++
ZK945.9 445 ststvttspstspvtstvtssssssttvttptsteststspsstvttstt 494
..................................................
++++++++++++++++++ +++ +++ ++++++++++++++++++++++
ZK945.9 495 apststtgpssssstpsstasssvsstasstqsststqqsstttksettt 544
..................................................
++++++++ ++ +++ ++++ + + +++ + + +++ + ++++++
ZK945.9 545 ssdgtnpdfyfvekatttfydstsvnltlnsglgiigyqtsiectsptss 594
..................................................
+ ++++++ +++ + ++ +++ + ++ ++++ + + + ++++++
ZK945.9 595 nyvsttkdgacftksvsmprlggtypastfvgpgnytfratmttddkkvy 644
..................................................
+ + ++ ++++ +++++++ +++++++++++++ ++++ +++++
ZK945.9 645 ytyanvyiqeyssttiesesstsavasstsstpstpsstlststvtepss 694
..................................................
++++++++++ +++++ ++++++++++++++++++ ++++++++++++++
ZK945.9 695 trssdstttsagstttlqestttseesttdsstttisdtsttssspsstt 744
..................................................
+++++ + ++ + +++ + +++++++++ + + +++ ++++++++
ZK945.9 745 adststlsvdqfdfildsglswnetrhnedsinivplptnaitptersqt 794
..................................................
+ ++ ++++ ++++ + +++ + + +++ + ++ ++ + ++
ZK945.9 795 fecrnvstepfliikestclnysntvlnatyssnipiqpietflvgigty 844
..................................................
+ + + ++ ++ + ++ + + +++++++ +++++++++++++ ++
ZK945.9 845 efrinmtdlttmqvvshiftlnvvadststsevtsttstgsssessaist 894
..................................................
+++ +++++ + ++++ +++++++++++++++++++ +++++++++++++
ZK945.9 895 tsgieststleasttdasqdsststsdsgttsdsttidssnstpstsdss 944
..................................................
+ +++++++++ +++ ++++ +++ +++++ + ++ + +++ ++++
ZK945.9 945 glsqtpsdsssasdsmrtttvdpdastetpydfvlenltwnetvyysenp 994
..................................................
++ ++++++ ++ + + +++++++ ++++ ++ ++++ +
ZK945.9 995 fyitpipnkepgalttamtcqcrndssqpfvllkesncltefgkngaysa 1044
..................................................
+ + ++ ++ + +++ + + +++ ++++ ++ + + ++++++++
ZK945.9 1045 svsfnpmtsfvpatgtyeflinvtnrasgesashiftmnvvlpttttetp 1094
..................................................
+++ +++++ ++++++++ ++++++++++++ ++ ++++ +++++++++
ZK945.9 1095 pttvsssddaggktggtgatggtggtgsggsattlstgdavrsttsgsgs 1144
..................................................
++++++++ ++++++ +++++++++++++++ ++++++ +++++++++
ZK945.9 1145 gqsstgsgaggsgttasgsgsggssgtgsdgvnsgkttalngdgtgsgta 1194
..................................................
++++++ ++++++++++++++++++ ++++++++++++++++++ ++ +
ZK945.9 1195 ttpgshlgdggstsgsgsdsngssgvstksssgsdtsgssdssgangafs 1244
..................................................
+ ++++++++++++ + ++ + ++ + ++ + ++ + +++ +
ZK945.9 1245 ataqpstrttktrsslatvspisaaeqaiidaqkadvmnqlagimdgsas 1294
............................................fe.lrt
+++ +++++ ++ ++ + + + ++ +++ + ++ ++ ++ + l+t
ZK945.9 1295 nnslntsssllnqisslpaadlvevaqsllsntlkipgvgnmssVDvLKT 1344
lGWklqslgrs<-*
l + + ++
ZK945.9 1345 L---QDNIATT 1352
COX2: domain 1 of 1, from 1632 to 1651: score 5.0, E = 3.3
*->MPIviEsvslkkFlnWlasq<-*
MPIviE v+l F + + +
ZK945.9 1632 MPIVIENVNLALFNQTTSPL 1651
GPS: domain 1 of 1, from 2071 to 2120: score 60.1, E = 3.5e-15
*->snpiCvfWdeselslgvWstdrGCelvetskpshttCsCnHLTsFAv
++ C+f+++++ +v+++ +G+++++++++++++Cs++HLT+F+v
ZK945.9 2071 VSKGCYFYQKTS---DVFNS-EGMYPSDGQGMQFVNCSTDHLTMFSV 2113
Lmdvspn<-*
+++++++
ZK945.9 2114 GAFNPTI 2120
PLAT: domain 1 of 1, from 2182 to 2307: score 92.5, E = 2.5e-26
*->vsyqlivatggstgagttgkvgislyGeegesekipldkgelkslpt
+ y + v tg +++a+t++++++ l G+eg+++ + + + e +
ZK945.9 2182 YMYVIAVETGYRMFATTDSTICFNLSGNEGDQIFRSFRSEEDG-NWE 2227
lgagpgstfsftfdvdedlGelgavriknehsglnswsptspewflksIt
+ + +g+t++f +++ + lGel+ +r++ + +gl+ ++ +w++++I+
ZK945.9 2228 FPFSWGTTDRFVMTTAFPLGELEYMRLWLDDAGLD----HRESWYCNRII 2273
VedgptqgkvhFpcnsWvyga.tg.deylslrif<-*
V+d++tq++++Fp n+W+ ++ +++++ r++
ZK945.9 2274 VKDLQTQDIYYFPFNNWLGTKnGDgETERLARVE 2307
ion_trans: domain 2 of 2, from 2894 to 3062: score 32.8, E = 1e-07
*->ileildyvftviFtlEmllkiialgfklhsr.iprkYlrspwnilDf
i l ++ ++ +t+ + +a+ ++ +++ + l++ n+ +
ZK945.9 2894 IVGALAVASVLAYTIRQRTTNRAMEDFNANNgNSYINLTEQRNWEIV 2940
lvvlpslislilflsgggsvklirlreslflalsevsygilsvlrllRll
+++++ + ++f+s +
ZK945.9 2941 FSYCLA--GAVFFTSCK--------------------------------- 2955
RvLRllrllrrapglfefelrtlGWklqslgrslkslfnlllllllllfi
++r+lr++++ +++l +l ++l +++++++ +l++ +
ZK945.9 2956 ----MIRILRFNRR-----IGVL---AATLDNALGAIVSFGIAFLFFSMT 2993
faiigvqlfggelnkccnpingntnFdnfgeaflwlFqtlTteGwgdimp
f +++ + g++ +++ + f +++ + + + +
ZK945.9 2994 FNSVLYAVLGNK----------MGGYRSLMATFQTALAGMLGKLDVTSIQ 3033
dtlagtvlgkiyfvifiilggflllNlfiavi<-*
+ + ++ +++++++i g+ l+l l++ +i
ZK945.9 3034 PI---SQFAFVVIMLYMIAGSKLVLQLYVTII 3062